ASCL1 (NM_004316) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201123L3V

Lenti ORF particles, ASCL1 (Myc-DDK tagged) - Human achaete-scute complex homolog 1 (Drosophila) (ASCL1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ASCL1
• Synonyms: ASH1; bHLHa46; HASH1; MASH1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_004316
• ORF Size: 708 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201123).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_004316.2
• RefSeq Size: 2490 bp
• RefSeq ORF: 711 bp
• Locus ID: 429
• UniProt ID: P50553
• Cytogenetics: 12q23.2
• Domains: HLH
• Protein Families: Druggable Genome, Transcription Factors
• MW: 25.5 kDa
• Gene Summary: This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]