DNA Polymerase epsilon (POLE3) (NM_017443) Human Tagged ORF Clone Lentiviral Particle

SKU RC200874L3V

Lenti ORF particles, POLE3 (Myc-DDK tagged) - Human polymerase (DNA directed), epsilon 3 (p17 subunit) (POLE3), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: DNA Polymerase epsilon
• Synonyms: CHARAC17; CHRAC2; CHRAC17; p17; YBL1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200874).
• ACCN: NM_017443
• ORF Size: 441 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_017443.3
• RefSeq Size: 2288 bp
• RefSeq ORF: 444 bp
• Locus ID: 54107
• UniProt ID: Q9NRF9
• Cytogenetics: 9q32
• Domains: CBFD_NFYB_HMF
• Protein Pathways: Base excision repair, DNA replication, Metabolic pathways, Nucleotide excision repair, Purine metabolism, Pyrimidine metabolism
• MW: 16.9 kDa
• Summary: POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]