HMGB2 (NM_002129) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200750L2V

Lenti ORF particles, HMGB2 (mGFP-tagged) - Human high mobility group box 2 (HMGB2), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: HMGB2
• Synonyms: HMG2
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_002129
• ORF Size: 627 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200750).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002129.2
• RefSeq Size: 1527 bp
• RefSeq ORF: 630 bp
• Locus ID: 3148
• UniProt ID: P26583
• Cytogenetics: 4q34.1
• Domains: HMG
• Protein Families: Druggable Genome, Transcription Factors
• MW: 24 kDa
• Gene Summary: This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008]