Cathepsin D (CTSD) (NM_001909) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200719L3V

Lenti ORF particles, CTSD (Myc-DDK tagged) - Human cathepsin D (CTSD), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: CTSD
• Synonyms: CLN10; CPSD; HEL-S-130P
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001909
• ORF Size: 1236 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200719).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001909.3
• RefSeq Size: 2141 bp
• RefSeq ORF: 1239 bp
• Locus ID: 1509
• UniProt ID: P07339
• Cytogenetics: 11p15.5
• Domains: asp
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome
• MW: 44.6 kDa
• Gene Summary: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]