NMT1 (NM_021079) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200594L2V

Lenti ORF particles, NMT1 (mGFP-tagged) - Human N-myristoyltransferase 1 (NMT1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: NMT1
• Synonyms: NMT
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_021079
• ORF Size: 1488 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200594).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_021079.3
• RefSeq Size: 4903 bp
• RefSeq ORF: 1491 bp
• Locus ID: 4836
• UniProt ID: P30419
• Cytogenetics: 17q21.31
• Domains: NMT
• Protein Families: Druggable Genome
• MW: 56.6 kDa
• Gene Summary: Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008]