MCL1 (NM_021960) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200521L4V

Lenti ORF particles, MCL1 (mGFP-tagged) - Human myeloid cell leukemia sequence 1 (BCL2-related) (MCL1), nuclear gene encoding mitochondrial protein, transcript variant 1, 200ul, >10^7 TU/mL

Product Images

RC200521L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC200521L4V particle to overexpress human MCL1-mGFP fusion protein.

• 

  RC200521L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC200521L4V particle to overexpress human MCL1-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: MCL1
• Synonyms: bcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1-ES; mcl1/EAT; MCL1L; MCL1S; TM
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_021960
• ORF Size: 1050 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200521).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_021960.3
• RefSeq Size: 4020 bp
• RefSeq ORF: 1053 bp
• Locus ID: 4170
• UniProt ID: Q07820
• Cytogenetics: 1q21.2
• Domains: Bcl-2
• Protein Families: Druggable Genome, Transmembrane
• MW: 37.2 kDa
• Gene Summary: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]