AKR1B1 (NM_001628) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200504L4V

Lenti ORF particles, AKR1B1 (mGFP-tagged) - Human aldo-keto reductase family 1, member B1 (aldose reductase) (AKR1B1), 200ul, >10^7 TU/mL

Product Images

RC200504L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC200504L4V particle to overexpress human AKR1B1-mGFP fusion protein.

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  RC200504L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC200504L4V particle to overexpress human AKR1B1-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: AKR1B1
• Synonyms: ADR; ALDR1; ALR2; AR
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001628
• ORF Size: 948 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200504).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001628.2
• RefSeq Size: 1416 bp
• RefSeq ORF: 951 bp
• Locus ID: 231
• UniProt ID: P15121
• Cytogenetics: 7q33
• Domains: aldo_ket_red
• Protein Families: Druggable Genome
• Protein Pathways: Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Metabolic pathways, Pentose and glucuronate interconversions, Pyruvate metabolism
• MW: 35.7 kDa
• Gene Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]