Chromogranin A (CHGA) (NM_001275) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200492L3V

Lenti ORF particles, CHGA (Myc-DDK tagged) - Human chromogranin A (parathyroid secretory protein 1) (CHGA), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: Chromogranin A
• Synonyms: CGA
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001275
• ORF Size: 1371 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200492).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001275.2
• RefSeq Size: 2079 bp
• RefSeq ORF: 1374 bp
• Locus ID: 1113
• UniProt ID: P10645
• Cytogenetics: 14q32.12
• Domains: Granin
• Protein Families: Druggable Genome, Secreted Protein
• MW: 50.7 kDa
• Gene Summary: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]