CNTF Receptor alpha (CNTFR) (NM_147164) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200487L2V

Lenti ORF particles, CNTFR (mGFP-tagged) - Human ciliary neurotrophic factor receptor (CNTFR), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CNTFR
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_147164
• ORF Size: 1116 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200487).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_147164.1
• RefSeq Size: 2070 bp
• RefSeq ORF: 1119 bp
• Locus ID: 1271
• UniProt ID: P26992
• Cytogenetics: 9p13.3
• Domains: ig, IGc2, IG, FN3
• Protein Families: Druggable Genome
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• MW: 40.6 kDa
• Gene Summary: This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]