RAB6A (NM_002869) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC200432L3V
- LentiORF®
Lenti ORF particles, RAB6A (Myc-DDK tagged) - Human RAB6A, member RAS oncogene family (RAB6A), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | RAB6A |
Synonyms | RAB6 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_002869 |
ORF Size | 624 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC200432).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002869.4 |
RefSeq Size | 3419 bp |
RefSeq ORF | 627 bp |
Locus ID | 5870 |
UniProt ID | P20340 |
Cytogenetics | 11q13.4 |
Domains | ras, RAN, RAS, RHO, RAB |
Protein Families | Druggable Genome |
MW | 23.5 kDa |
Gene Summary | This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
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