LSM1 (NM_014462) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200288L1V

Lenti ORF particles, LSM1 (Myc-DDK tagged) - Human LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) (LSM1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: LSM1
• Synonyms: CASM; YJL124C
• Mammalian Cell Selection: None
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_014462
• ORF Size: 399 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200288).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_014462.2
• RefSeq Size: 1161 bp
• RefSeq ORF: 402 bp
• Locus ID: 27257
• UniProt ID: O15116
• Cytogenetics: 8p11.23
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: RNA degradation
• MW: 15.2 kDa
• Gene Summary: This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011]