DUS2L (DUS2) (NM_017803) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC200175L4V

Lenti ORF particles, DUS2 (mGFP-tagged) - Human dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae) (DUS2L), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: DUS2
• Synonyms: DUS2L; SMM1; URLC8
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_017803
• ORF Size: 1479 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200175).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_017803.3
• RefSeq Size: 2342 bp
• RefSeq ORF: 1482 bp
• Locus ID: 54920
• UniProt ID: Q9NX74
• Cytogenetics: 16q22.1
• Domains: DSRM, Dus
• MW: 55.1 kDa
• Gene Summary: This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]