Ace2 (NM_027286) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR227195L4V

Lenti ORF particles, Ace2 (GFP-tagged) - Mouse angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (Ace2), transcript variant 2, 200ul, >10^7 TU/mL

Product Images

MR227195L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with MR227195L4V particle to overexpress human Ace2-mGFP fusion protein.

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Ace2
• Synonyms: 2010305L05Rik
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_027286
• ORF Size: 2415 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR227195).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_027286.4, NP_081562.2
• RefSeq Size: 3418 bp
• RefSeq ORF: 2418 bp
• Locus ID: 70008
• UniProt ID: Q8R0I0
• Cytogenetics: X 76.12 cM
• Gene Summary: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. May have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19, regulating its trafficking on the cell surface and its activity (PubMed:19185582).[UniProtKB/Swiss-Prot Function]