Trip13 (NM_027182) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR227183L3V
- LentiORF®
Lenti ORF particles, Trip13 (Myc-DDK-tagged) - Mouse thyroid hormone receptor interactor 13 (Trip13), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Trip13 |
Synonyms | 2410002G23Rik; D13Ertd328e |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_027182 |
ORF Size | 1299 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR227183).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_027182.2, NP_081458.1 |
RefSeq Size | 2267 bp |
RefSeq ORF | 1299 bp |
Locus ID | 69716 |
UniProt ID | Q3UA06 |
Cytogenetics | 13 40.15 cM |
Gene Summary | Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (PubMed:17696610, PubMed:19851446, PubMed:20711356). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (By similarity).[UniProtKB/Swiss-Prot Function] |
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