Myd88 (NM_010851) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR227105L3V

  • LentiORF®

Lenti ORF particles, Myd88 (Myc-DDK-tagged) - Mouse myeloid differentiation primary response gene 88 (Myd88), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK w/ Puro mGFP w/ Puro


Biosafety Sheet


Interest in protein/lysate? Submit request here!

Buy this product and get 50% off on the Lenti RapidTiter kit. Use Code: Rapid50

USD 1,000.00

7 Weeks*

Size
    • 200 ul

Product Images

Frequently bought together (2)
Lenti ORF control particles of pLenti-C-Myc-DDK-P2A-Puro, >1x10^7 TU/ml, 0.5 ml
    • 500 ul

USD 365.00


One-Wash Lentivirus Titer Kit, HIV-1 p24 ELISA
    • 96 reactions

USD 671.00

Other products for "Myd88"

Specifications

Product Data
Type Mouse Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Symbol Myd88
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_010851
ORF Size 888 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR227105).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_010851.2
RefSeq Size 1947 bp
RefSeq ORF 891 bp
Locus ID 17874
UniProt ID P22366
Cytogenetics 9 71.33 cM
Gene Summary Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response (PubMed:9697844). Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:9575168, PubMed:9697844). Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway (PubMed:9697844). Isoform 2 is defective in its ability to induce IRAK phosphorylation and NF-kappa-B activation and can function as a negative regulator of activation by IL-1 or lipopolysaccharide (LPS) (PubMed:11909531). Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (PubMed:17018642). MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (PubMed:17635956, PubMed:21998396). Mediates leukocyte recruitment at the inflammatory site (PubMed:18941239).[UniProtKB/Swiss-Prot Function]

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.