Bmpr2 (NM_007561) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR226598L3V

Lenti ORF particles, Bmpr2 (Myc-DDK-tagged) - Mouse bone morphogenic protein receptor, type II (serine/threonine kinase) (Bmpr2), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Bmpr2
• Synonyms: 2610024H22Rik; AL117858; AW546137; BB189135; BM; BMP; BMP-; BMP-2; BMPR-2; BMPR-II; BMPRII; BRK-3; Gm20272
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR226598).
• ACCN: NM_007561
• ORF Size: 3114 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_007561.4, NP_031587.1
• RefSeq Size: 3507 bp
• RefSeq ORF: 3117 bp
• Locus ID: 12168
• UniProt ID: O35607
• Cytogenetics: 1 C2
• Summary: This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important during embryonic development. Mutations in this gene can cause pulmonary hypertension. [provided by RefSeq, Mar 2013]