Fanci (NM_145946) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR221899L4V

Lenti ORF particles, Fanci (GFP-tagged) - Mouse Fanconi anemia, complementation group I (Fanci), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Fanci
• Synonyms: MGC38195; MGC38407
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_145946
• ORF Size: 3990 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR221899).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_145946.2, NP_666058.2
• RefSeq Size: 4621 bp
• RefSeq ORF: 3993 bp
• Locus ID: 208836
• UniProt ID: Q8K368
• Cytogenetics: 7 D2
• Gene Summary: Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites. Required for maintenance of chromosomal stability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participates in S phase and G2 phase checkpoint activation upon DNA damage.[UniProtKB/Swiss-Prot Function]