Lima1 (NM_023063) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR221683L4V
- LentiORF®
Lenti ORF particles, Lima1 (GFP-tagged) - Mouse LIM domain and actin binding 1 (Lima1), transcript variant b, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Lima1 |
Synonyms | Eplin |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_023063 |
ORF Size | 1779 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR221683).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_023063.3, NP_075550.2 |
RefSeq Size | 4110 bp |
RefSeq ORF | 1782 bp |
Locus ID | 65970 |
Cytogenetics | 15 56.13 cM |
Gene Summary | Actin-binding protein involved in actin cytoskeleton regulation and dynamics. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments (By similarity). Plays a role in cholesterol homeostasis. Influences plasma cholesterol levels through regulation of intestinal cholesterol absorption. May act as a scaffold protein by regulating NPC1L1 transportation, an essential protein for cholesterol absorption, to the plasma membrane by recruiting MYO5B to NPC1L1, and thus facilitates cholesterol uptake (PubMed:29880681).[UniProtKB/Swiss-Prot Function] |
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