Rnf125 (NM_026301) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR220681L3V

  • LentiORF®

Lenti ORF particles, Rnf125 (Myc-DDK-tagged) - Mouse ring finger protein 125 (Rnf125), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK w/ Puro mGFP w/ Puro

AAV Particle: DDK



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USD 700.00

7 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag Myc-DDK
Symbol Rnf125
Synonyms 4930553F04Rik
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_026301
ORF Size 420 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR220681).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_026301.2
RefSeq Size 1334 bp
RefSeq ORF 423 bp
Locus ID 67664
UniProt ID Q9D9R0
Cytogenetics 18 A2
Gene Summary E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as DDX58/RIG-I, MAVS/IPS1, IFIH1/MDA5, JAK1 and p53/TP53. Acts as a negative regulator of type I interferon production by mediating ubiquitination of DDX58/RIG-I at 'Lys-181', leading to DDX58/RIG-I degradation. Mediates ubiquitination and subsequent degradation of p53/TP53. Mediates ubiquitination and subsequent degradation of JAK1. Acts as a positive regulator of T-cell activation.[UniProtKB/Swiss-Prot Function]

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