H2 (H2-Ke6) (NM_013543) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR218574L4V

Lenti ORF particles, H2 (GFP-tagged) - Mouse H2-K region expressed gene 6 (H2-Ke6), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: H2-Ke6
• Synonyms: D17H6S112E; H-2Ke6; Hsd17b8; Ke-6; Ke6; Ring2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_013543
• ORF Size: 780 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR218574).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013543.2, NP_038571.2
• RefSeq Size: 981 bp
• RefSeq ORF: 780 bp
• Locus ID: 14979
• UniProt ID: P50171
• Cytogenetics: 17 17.98 cM
• Gene Summary: NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone (PubMed:9712896). The heterotetramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD.[UniProtKB/Swiss-Prot Function]