Hsd3b7 (NM_133943) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR218387L4V

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  • LentiORF®

Lenti ORF particles, Hsd3b7 (GFP-tagged) - Mouse hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 (Hsd3b7), transcript variant 1, 200ul, >10^7 TU/mL



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USD 1,007.00

6 Weeks*

Size
    • 200 ul

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Frequently bought together (2)
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Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag mGFP
Symbol Hsd3b7
Synonyms AI195443; BB098564
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_133943
ORF Size 1110 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR218387).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_133943.2, NP_598704.2
RefSeq Size 1823 bp
RefSeq ORF 1110 bp
Locus ID 101502
UniProt ID Q9EQC1
Cytogenetics 7 F3
Gene Summary The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis (PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (PubMed:22999953).[UniProtKB/Swiss-Prot Function]
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