Tsen15 (NM_025677) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR215931L3V
- LentiORF®
Lenti ORF particles, Tsen15 (Myc-DDK-tagged) - Mouse tRNA splicing endonuclease 15 homolog (S. cerevisiae) (Tsen15), 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Tsen15 |
Synonyms | 5730449L18Rik; AL023077; Sen15 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_025677 |
ORF Size | 504 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR215931).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_025677.3, NP_079953.2 |
RefSeq Size | 1147 bp |
RefSeq ORF | 507 bp |
Locus ID | 66637 |
UniProt ID | Q8R3W5 |
Cytogenetics | 1 G2 |
Gene Summary | Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events (By similarity).[UniProtKB/Swiss-Prot Function] |
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