Bcl2 (NM_009741) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR212128L4V
- LentiORF®
Lenti ORF particles, Bcl2 (GFP-tagged) - Mouse B-cell leukemia/lymphoma 2 (Bcl2), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK w/ Puro
AAV Particle: DDK
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Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | mGFP |
Symbol | Bcl2 |
Synonyms | AW986256; Bcl-; Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_009741 |
ORF Size | 708 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR212128).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009741.3, NP_033871.2 |
RefSeq Size | 7206 bp |
RefSeq ORF | 711 bp |
Locus ID | 12043 |
UniProt ID | P10417 |
Cytogenetics | 1 49.76 cM |
Gene Summary | This gene encodes a member of the B cell lymphoma 2 protein family. Members of this family regulate cell death in multiple cell types and can have either proapoptotic or antiapoptotic activities. The protein encoded by this gene inhibits mitochondrial-mediated apoptosis. This protein is an integral outer mitochondrial membrane protein that functions as part of signaling pathway that controls mitochondrial permeability in response to apoptotic stimuli. This protein may also play a role in neuron cell survival and autophagy. Abnormal expression and chromosomal translocations of this gene are associated with cancer progression in numerous tissues. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
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