Shkbp1 (NM_138676) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR210149L3V

Lenti ORF particles, Shkbp1 (Myc-DDK-tagged) - Mouse Sh3kbp1 binding protein 1 (Shkbp1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Product Name: Shkbp1 (NM_138676) Mouse Tagged ORF Clone Lentiviral Particle
• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Shkbp1
• Synonyms: B930062H15Rik; Sb1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_138676
• ORF Size: 2112 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR210149).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_138676.2, NP_619617.2
• RefSeq Size: 2347 bp
• RefSeq ORF: 2115 bp
• Locus ID: 192192
• Cytogenetics: 7 A3
• Gene Summary: Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation (PubMed:21830225).[UniProtKB/Swiss-Prot Function]