Keap1 (NM_001110307) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR209525L2V

  • LentiORF®

Lenti ORF particles, Keap1 (GFP-tagged) - Mouse kelch-like ECH-associated protein 1 (Keap1), transcript variant 4, 200ul, >10^7 TU/mL

Lentiviral Particles: DDK DDK w/ Puro mGFP mGFP w/ Puro



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USD 1,422.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Mouse Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol Keap1
Synonyms INRF2; mKIAA0132
Mammalian Cell Selection None
Vector pLenti-C-mGFP
ACCN NM_001110307
ORF Size 1875 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR209525).
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001110307.1, NP_001103777.1
RefSeq Size 3151 bp
RefSeq ORF 1875 bp
Locus ID 50868
UniProt ID Q9Z2X8
Cytogenetics 9 A3
Gene Summary Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).[UniProtKB/Swiss-Prot Function]

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