Atp6v1a (NM_007508) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR209449L4V

Lenti ORF particles, Atp6v1a (GFP-tagged) - Mouse ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Atp6v1a
• Synonyms: AI647066; Atp6a1; Atp6a2; Atp6v1a1; VA68; VPP2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_007508
• ORF Size: 1851 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR209449).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007508.4
• RefSeq Size: 3947 bp
• RefSeq ORF: 1854 bp
• Locus ID: 11964
• UniProt ID: P50516
• Cytogenetics: 16 B4
• Gene Summary: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in neurite development and synaptic connectivity.[UniProtKB/Swiss-Prot Function]