Ric8a (NM_053194) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR208493L4V

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  • LentiORF®

Lenti ORF particles, Ric8 (GFP-tagged) - Mouse resistance to inhibitors of cholinesterase 8 homolog (C. elegans) (Ric8), 200ul, >10^7 TU/mL



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USD 1,044.00

6 Weeks*

Size
    • 200 ul

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Frequently bought together (2)
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Other products for "Ric8a"

Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag mGFP
Symbol Ric8a
Synonyms AI114950; RIC-8; Ric8
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_053194
ORF Size 1593 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR208493).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_053194.4, NP_444424.1
RefSeq Size 2967 bp
RefSeq ORF 1593 bp
Locus ID 101489
UniProt ID Q3TIR3
Cytogenetics 7 F4
Gene Summary Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation (By similarity).[UniProtKB/Swiss-Prot Function]
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