Becn1 (NM_019584) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR207162L4V

  • LentiORF®

Lenti ORF particles, Becn1 (GFP-tagged) - Mouse beclin 1, autophagy related (Becn1), 200ul, >10^7 TU/mL

Lentiviral Particles: DDK w/ Puro mGFP w/ Puro



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USD 1,236.00

2 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag mGFP
Symbol Becn1
Synonyms 4921513J16Rik; 5430417M23Rik; Atg6
Mammalian Cell Selection Puromycin
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_019584
ORF Size 1344 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR207162).
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_019584.3
RefSeq Size 2031 bp
RefSeq ORF 1347 bp
Locus ID 56208
UniProt ID O88597
Cytogenetics 11 D
Gene Summary Plays a central role in autophagy (PubMed:10604474, PubMed:12372286, PubMed:19270693, PubMed:28445460). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis (PubMed:19270693, PubMed:25275521). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms (PubMed:25275521). Involved in endocytosis including endosome formation in neuronal cells (PubMed:25275521). May play a role in antiviral host defense (By similarity).[UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.