Cr1l (NM_013499) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR207025L4V

Lenti ORF particles, Cr1l (GFP-tagged) - Mouse complement component (3b/4b) receptor 1-like (Cr1l), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Cr1l
• Synonyms: Crry; Mcp; mCRY
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_013499
• ORF Size: 1323 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR207025).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_013499.2, NP_038527.2
• RefSeq Size: 1674 bp
• RefSeq ORF: 1323 bp
• Locus ID: 12946
• UniProt ID: Q64735
• Cytogenetics: 1 98.43 cM
• Gene Summary: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.[UniProtKB/Swiss-Prot Function]