Lipa (NM_001111100) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR206231L3V

Lenti ORF particles, Lipa (Myc-DDK-tagged) - Mouse lysosomal acid lipase A (Lipa), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Lipa
• Synonyms: AA960673; Lal; Lip-1; Lip1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001111100
• ORF Size: 1191 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR206231).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001111100.1, NP_001104570.1
• RefSeq Size: 2987 bp
• RefSeq ORF: 1194 bp
• Locus ID: 16889
• UniProt ID: Q9Z0M5
• Cytogenetics: 19 C1
• Gene Summary: Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation (By similarity).[UniProtKB/Swiss-Prot Function]