Chrdl1 (NM_031258) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR204928L4V

Lenti ORF particles, Chrdl1 (GFP-tagged) - Mouse chordin-like 1 (Chrdl1), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Chrdl1
• Synonyms: CHL; CHL1; Nrln1; VOPT
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_031258
• ORF Size: 999 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR204928).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_031258.2, NP_112548.2
• RefSeq Size: 3291 bp
• RefSeq ORF: 1002 bp
• Locus ID: 83453
• UniProt ID: Q920C1
• Cytogenetics: X F2
• Gene Summary: Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation (By similarity). Antagonizes the function of BMP7 and may thus play an important role in the embryonic bone formation. Shows no inhibitory effect on the inducing activity of BMP2. Plays a role during anterior segment eye development (By similarity).[UniProtKB/Swiss-Prot Function]