Ufd1l (Ufd1) (NM_011672) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR204334L3V

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  • LentiORF®

Lenti ORF particles, Ufd1l (Myc-DDK-tagged) - Mouse ubiquitin fusion degradation 1 like (Ufd1l), transcript variant 1, 200ul, >10^7 TU/mL



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USD 720.00


Availability*
6 Weeks

Size
    • 200 ul


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Specifications

Product Data
Product Name Ufd1l (Ufd1) (NM_011672) Mouse Tagged ORF Clone Lentiviral Particle
Type Mouse Tagged ORF Clone
Tag Myc-DDK
Symbol Ufd1
Synonyms Ufd1; Ufd1l
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_011672
ORF Size 924 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR204334).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_011672.2, NP_035802.2, NP_035802.3
RefSeq Size 1996 bp
RefSeq ORF 924 bp
Locus ID 22230
UniProt ID P70362
Cytogenetics 16 11.65 cM
Gene Summary Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures (By similarity). Acts as a negative regulator of type I interferon production via the complex formed with VCP and NPLOC4, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I (By similarity).[UniProtKB/Swiss-Prot Function]
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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