Fbxo2 (NM_176848) Mouse Tagged ORF Clone Lentiviral Particle

  • LentiORF®
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SKU
MR204114L3V
Lenti ORF particles, Fbxo2 (Myc-DDK-tagged) - Mouse F-box protein 2 (Fbxo2), 200ul, >10^7 TU/mL
  $850.00
5 Weeks*
Specifications
Specifications
Product Data
Type Mouse Tagged ORF Clone Lentiviral Particle
Tag Myc-DDK
Target Symbol Fbxo2
Synonyms FBG1; Fbs1; Fbs2; FBX2; NFB42; Prpl4
Vector pLenti-C-Myc-DDK-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR204114).
ACCN NM_176848
ORF Size 891 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_176848.1, NP_789818.1
RefSeq Size 1260 bp
RefSeq ORF 894 bp
Locus ID 230904
UniProt ID Q80UW2
Cytogenetics 4 78.68 cM
Summary Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.UniProtKB/Swiss-Prot Function
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.