Cd274 (NM_021893) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR203953L1V

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  • LentiORF®

Lenti ORF particles, Cd274 (Myc-DDK-tagged) - Mouse CD274 antigen (Cd274), 200ul, >10^7 TU/mL

  View "NM_021893" in other vectors (10)

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USD 930.00

6 Weeks

    • 200 ul

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Product Data
Product Name Cd274 (NM_021893) Mouse Tagged ORF Clone Lentiviral Particle
Symbol Cd274
Synonyms A530045L16Rik; B7h1; Pdcd1l1; Pdcd1lg1; Pdl1
Vector pLenti-C-Myc-DDK
ACCN NM_021893
ORF Size 873 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR203953).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_021893.3, NP_068693
RefSeq Size 3653
RefSeq ORF 873
Locus ID 60533
Cytogenetics 19 C1
Gene Summary The protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Mice deficient for this gene display a variety of phenotypes including decreased allogeneic fetal survival rates and severe experimental autoimmune encephalomyelitis. [provided by RefSeq, Sep 2015]

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Customer Reviews 
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