Hmox1 (NM_010442) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR203944L4V

Lenti ORF particles, Hmox1 (GFP-tagged) - Mouse heme oxygenase (decycling) 1 (Hmox1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Hmox1
• Synonyms: D8Wsu38e; Hemox; Hmox; HO-1; HO1; Hsp32
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_010442
• ORF Size: 867 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR203944).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_010442.1
• RefSeq Size: 1564 bp
• RefSeq ORF: 870 bp
• Locus ID: 15368
• UniProt ID: P14901
• Cytogenetics: 8 C1
• Gene Summary: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.[UniProtKB/Swiss-Prot Function]