March1 (NM_175188) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR203875L3V

Lenti ORF particles, March1 (Myc-DDK-tagged) - Mouse membrane-associated ring finger (C3HC4) 1 (March1), transcript variant 3, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: March1
• Synonyms: 2900024D24Rik; BB085186
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_175188
• ORF Size: 858 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR203875).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_175188.3
• RefSeq Size: 4391 bp
• RefSeq ORF: 858 bp
• Locus ID: 72925
• UniProt ID: Q6NZQ8
• Cytogenetics: 8 B3.1
• Gene Summary: E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell surface localization thus sequestering them in the intracellular endosomal system.[UniProtKB/Swiss-Prot Function]