Ufm1 (NM_026435) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR200184L3V

Lenti ORF particles, Ufm1 (Myc-DDK-tagged) - Mouse ubiquitin-fold modifier 1 (Ufm1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: Ufm1
• Synonyms: 1810045K17Rik; AI132708; AI463323; ENSMUSG00000074598; Gm10726
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_026435
• ORF Size: 255 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR200184).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_026435.5, NP_080711.1
• RefSeq Size: 4887 bp
• RefSeq ORF: 258 bp
• Locus ID: 67890
• UniProt ID: P61961
• Cytogenetics: 3 C
• Gene Summary: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to substrate proteins as a monomer or a lysine-linked polymer (PubMed:21494687). The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1. This post-translational modification on lysine residues of proteins may play a crucial role in a number of cellular processes. TRIP4 ufmylation may for instance play a role in nuclear receptors-mediated transcription (By similarity). Other substrates may include DDRGK1 with which it may play a role in the cellular response to endoplasmic reticulum stress.[UniProtKB/Swiss-Prot Function]