IL20 Receptor alpha (IL20RA) (NM_001278722) Human Untagged Clone
IL20RA (untagged) - Human interleukin 20 receptor, alpha (IL20RA), transcript variant 2
|Product Name||IL20 Receptor alpha (IL20RA) (NM_001278722) Human Untagged Clone|
|Type||Human Untagged Clone|
|Synonyms||CRF2-8; IL-20R-alpha; IL-20R1; IL-20RA|
|E. coli Selection||Kanamycin (25 ug/mL)|
>NCBI ORF sequence for NM_001278722, the custom clone sequence may differ by one or more nucleotides
|OTI Disclaimer||Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).|
|Product Components||The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.|
|Reconstitution||1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
|RefSeq Size||3382 bp|
|RefSeq ORF||1515 bp|
|Protein Families||Druggable Genome, Transmembrane|
|Protein Pathways||Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway|
|Gene Summary||This gene encodes a member of the type II cytokine receptor family. The encoded protein is a subunit of the receptor for interleukin 20, a cytokine that may be involved in epidermal function. The interleukin 20 receptor is a heterodimeric complex consisting of the encoded protein and interleukin 20 receptor beta. This gene and interleukin 20 receptor beta are highly expressed in skin, and are upregulated in psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Transcript Variant: This variant (2) contains an alternate 5'-most exon, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
|cDNA Clone Resources|
|RC238599||IL20RA (myc-DDK-tagged) - Human interleukin 20 receptor, alpha (IL20RA), transcript variant 2||