IL1RAP (NM_001167928) Human Untagged Clone

CAT#: SC328932

IL1RAP (untagged)-Human interleukin 1 receptor accessory protein (IL1RAP) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL1RAP
• Synonyms: C3orf13; IL-1RAcP; IL1R3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001167928, the custom clone sequence may differ by one or more nucleotides
  ATGACACTTCTGTGGTGTGTAGTGAGTCTCTACTTTTATGGAATCCTGCAAAGTGATGCC
  TCAGAACGCTGCGATGACTGGGGACTAGACACCATGAGGCAAATCCAAGTGTTTGAAGAT
  GAGCCAGCTCGCATCAAGTGCCCACTCTTTGAACACTTCTTGAAATTCAACTACAGCACA
  GCCCATTCAGCTGGCCTTACTCTGATCTGGTATTGGACTAGGCAGGACCGGGACCTTGAG
  GAGCCAATTAACTTCCGCCTCCCCGAGAACCGCATTAGTAAGGAGAAAGATGTGCTGTGG
  TTCCGGCCCACTCTCCTCAATGACACTGGCAACTATACCTGCATGTTAAGGAACACTACA
  TATTGCAGCAAAGTTGCATTTCCCTTGGAAGTTGTTCAAAAAGACAGCTGTTTCAATTCC
  CCCATGAAACTCCCAGTGCATAAACTGTATATAGAATATGGCATTCAGAGGATCACTTGT
  CCAAATGTAGATGGATATTTTCCTTCCAGTGTCAAACCGACTATCACTTGGTATATGGGC
  TGTTATAAAATACAGAATTTTAATAATGTAATACCCGAAGGTATGAACTTGAGTTTCCTC
  ATTGCCTTAATTTCAAATAATGGAAATTACACATGTGTTGTTACATATCCAGAAAATGGA
  CGTACGTTTCATCTCACCAGGACTCTGACTGTAAAGGTAGTAGGCTCTCCAAAAAATGCA
  GTGCCCCCTGTGATCCATTCACCTAATGATCATGTGGTCTATGAGAAAGAACCAGGAGAG
  GAGCTACTCATTCCCTGTACGGTCTATTTTAGTTTTCTGATGGATTCTCGCAATGAGGTT
  TGGTGGACCATTGATGGAAAAAAACCTGATGACATCACTATTGATGTCACCATTAACGAA
  AGTATAAGTCATAGTAGAACAGAAGATGAAACAAGAACTCAGATTTTGAGCATCAAGAAA
  GTTACCTCTGAGGATCTCAAGCGCAGCTATGTCTGTCATGCTAGAAGTGCCAAAGGCGAA
  GTTGCCAAAGCAGCCAAGGTGAAGCAGAAAGTGCCAGCTCCAAGATACACAGTGGAACTG
  GCTTGTGGTTTTGGAGCCACAGTCCTGCTAGTGGTGATTCTCATTGTTGTTTACCATGTT
  TACTGGCTAGAGATGGTCCTATTTTACCGGGCTCATTTTGGAACAGATGAAACCATTTTA
  GATGGAAAAGAGTATGATATTTATGTATCCTATGCAAGGAATGCGGAAGAAGAAGAATTT
  GTATTACTGACCCTCCGTGGAGTTTTGGAGAATGAATTTGGATACAAGCTGTGCATCTTT
  GACCGAGACAGTCTGCCTGGGGGAATTGTCACAGATGAGACTTTGAGCTTCATTCAGAAA
  AGCAGACGCCTCCTGGTTGTTCTAAGCCCCAACTACGTGCTCCAGGGAACCCAAGCCCTC
  CTGGAGCTCAAGGCTGGCCTAGAAAATATGGCCTCTCGGGGCAACATCAACGTCATTTTA
  GTACAGTACAAAGCTGTGAAGGAAACGAAGGTGAAAGAGCTGAAGAGGGCTAAGACGGTG
  CTCACGGTCATTAAATGGAAAGGGGAAAAATCCAAGTATCCACAGGGCAGGTTCTGGAAG
  CAGCTGCAGGTGGCCATGCCAGTGAAGAAAAGTCCCAGGCGGTCTAGCAGTGATGAGCAG
  GGCCTCTCGTATTCATCTTTGAAAAATGTATGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001167928
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001167928.1, NP_001161400.1
• RefSeq Size: 4965 bp
• RefSeq ORF: 1713 bp
• Locus ID: 3556
• UniProt ID: Q9NPH3
• Cytogenetics: 3q28
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction
• Gene Summary: This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]
  Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. It encodes the membrane-bound isoform (1).