LRRFIP1 (NM_001137552) Human Untagged Clone

CAT#: SC325337

LRRFIP1 (untagged)-Human leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LRRFIP1
• Synonyms: FLAP-1; FLAP1; FLIIAP1; GCF-2; GCF2; HUFI-1; TRIP
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001137552, the custom clone sequence may differ by one or more nucleotides
  ATGACCAGCCCCGCGGCCGCTCAAAGCCGGGAGATCGACTGTTTGAGCCCGGAAGCGCAG
  AAGCTGGCGGAAGCCCGGCTCGCTGCAAAACGGGCGGCCCGCGCGGAGGCTCGCGAGATC
  CGCATGAAGGAGCTGGAGCGGCAGCAGAAGGAGGAAGACAGTGAGCGCTACTCTCGTAGA
  TCCAGAAGAAACACATCGGCTTCTGATGAAGACGAGCGCATGTCAGTGGGTAGTCGTGGA
  AGCCTGAGGGTAGAAGAGAGACCAGAAAAAGATTTTACTGAGAAGGGGTCTCGTAACATG
  CCGGGCCTGTCTGCAGCCACGCTGGCCTCTCTGGGTGGGACTTCCTCTCGGAGAGGCAGC
  GGAGACACCTCCATCTCCATCGACACCGAGGCATCCATCAGGGAAATCAAGGAACTCAAT
  GAGTTAAAGGACCAGATTCAGGATGTAGAAGGCAAATACATGCAGGGATTGAAAGAGATG
  AAGGACTCTCTAGCAGAAGTTGAAGAGAAATATAAGAAGGCTATGGTTTCCAATGCTCAG
  CTAGACAATGAAAAGACAAACTTCATGTACCAGGTTGATACCCTAAAAGATATGTTGCTG
  GAGCTTGAAGAACAGCTGGCTGAATCTAGGCGGCAGTACGAAGAGAAAAACAAAGAATTT
  GAAAGGGAAAAACACGCCCACAGTATACTGCAATTTCAGTTTGCTGAAGTCAAGGAGGCC
  CTGAAGCAAAGAGAGGAAATGCTCGAGAAACATGGAATAATCCTAAATTCAGAAATAGCT
  ACCAATGGAGAGACTTCCGACACCCTCAATAATGTTGGATACCAAGGTCCTACCAAGATG
  ACAAAAGAAGAGTTAAATGCCCTCAAGTCGACAGGGGATGGGACCCTAGGAAGAGCCAGT
  GAAGTGGAGGTGAAAAATGAAATCGTGGCGAATGTGGGGAAAAGAGAAATCTTGCACAAT
  ACTGAGAAAGAACAACACACAGAGGACACAGTGAAGGACTGTGTGGACATAGAGGTATTC
  CCTGCTGGTGAGAATACCGAGGACCAGAAATCCTCTGAAGACACTGCCCCATTCCTAGGA
  ACCTTAGCAGGTGCTACCTATGAGGAACAGGTTCAAAGCCAAATTCTTGAGAGCAGTTCT
  CTCCCTGAAAACACAGTACAGGTTGAGTCAAATGAGGTCATGGGTGCACCAGATGACAGG
  ACCAGAACTCCCCTTGAGCCATCCAACTGTTGGAGTGACTTAGATGGTGGGAACCACACA
  GAGAATGTGGGAGAGGCAGCAGTGACTCAGGTTGAAGAGCAGGCAGGCACAGTGGCCTCG
  TGTCCTTTAGGGCATAGTGATGACACAGTTTATCATGATGACAAATGTATGGTAGAGGTC
  CCCCAAGAGTTAGAGACAAGCACAGGGCATAGTTTAGAGAAAGAATTCACCAACCAGGAA
  GCAGCTGAGCCCAAGGAGGTTCCAGCGCACAGTACAGAAGTAGGTAGGGATCACAACGAA
  GAAGAGGGTGAAGAAACAGGATTAAGGGACGAGAAACCAATCAAGACAGAAGTTCCTGGT
  TCTCCAGCAGGAACTGAGGGCAACTGTCAGGAAGCGACAGGTCCAAGTACAGTAGACACT
  CAAAATGAACCCTTAGATATGAAAGAGCCCGATGAAGAAAAGAGTGACCAACAGGGAGAG
  GCATTGGACTCATCGCAGAAGAAGACAAAGAACAAGAAAAAGAAAAACAAGAAGAAAAAA
  TCCCCAGTACCCGTAGAAACCCTTAAAGATGTTAAAAAAGAGTTAACGTATCAGAACACA
  GATTTAAGTGAAATTAAGGAAGAAGAGCAGGTAAAGTCTACTGACAGAAAGTCAGCAGTG
  GAAGCCCAAAACGAGGTGACTGAAAATCCAAAACAGAAAATTGCAGCAGAAAGCAGTGAA
  AATGTTGATTGTCCGGAGAATCCTAAAATTAAGTTGGATGGAAAACTTGACCAAGAAGGT
  GATGATGTACAAACAGCAGCTGAGGAGGTACTAGCTGATGGAGACACATTAGATTTTGAG
  GATGACACCGTTCAATCATCAGGCCCGAGGGCTGGTGGTGAAGAATTAGATGAAGGTGTT
  GCAAAAGATAATGCTAAAATAGATGGTGCCACTCAAAGCAGTCCTGCAGAACCAAAGAGC
  GAAGACGCAGATCGCTGCACCCTGCCCGAACATGAAAGTCCCTCACAGGACATTAGTGAT
  GCCTGTGAAGCAGAAAGTACAGAGAGGTGTGAGATGTCAGAACATCCAAGTCAGACCGTC
  AGGAAAGCTTTAGACAGCAATAGCCTAGAGAACGATGACTTGTCGGCACCAGGAAGAGAG
  CCAGGGCACTTCAATCCAGAAAGCAGAGAAGATACCAGAGGAGGGAATGAGAAGGGCAAA
  AGCAAAGAAGACTGTACCATGTCC
  
• Restriction Sites: Please inquire
• ACCN: NM_001137552
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001137552.1, NP_001131024.1
• RefSeq Size: 4510 bp
• RefSeq ORF: 2427 bp
• Locus ID: 9208
• UniProt ID: Q32MZ4
• Cytogenetics: 2q37.3
• Protein Families: Transcription Factors
• Gene Summary: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (3) encodes the longest isoform (3).