ELAVL1 (NM_001419) Human Untagged Clone

CAT#: SC322158

ELAVL1 (untagged)-Human ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ELAVL1
• Synonyms: ELAV1; Hua; HUR; MelG
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322158 CCGTCGCCGCCACCGCCGCCACCGCTACCGAGGCCGAGCGGAGCCGTTAGCGCCGCGCCG
  CCGCCGCCTCCCGCCCGCCCCGGAGCAGCCCCGGGCCCGCCCGCCCGCATCCAGATTTTT
  GAAAAATACAATGTCTAATGGTTATGAAGACCACATGGCCGAAGACTGCAGGGGTGACAT
  CGGGAGAACGAATTTGATCGTCAACTACCTCCCTCAGAACATGACCCAGGATGAGTTACG
  AAGCCTGTTCAGCAGCATTGGTGAAGTTGAATCTGCAAAACTTATTCGGGATAAAGTAGC
  AGGACACAGCTTGGGCTATGGCTTTGTGAACTACGTGACCGCGAAGGATGCAGAGAGAGC
  GATCAACACGCTGAACGGCTTGAGGCTCCAGTCAAAAACCATTAAGGTGTCGTATGCTCG
  CCCGAGCTCAGAGGTGATCAAAGACGCCAACTTGTACATCAGCGGGCTCCCGCGGACCAT
  GACCCAGAAGGACGTAGAAGACATGTTCTCTCGGTTTGGGCGGATCATCAACTCGCGGGT
  CCTCGTGGATCAGACTACAGGTTTGTCCAGAGGGGTTGCGTTTATCCGGTTTGACAAACG
  GTCGGAGGCAGAAGAGGCAATTACCAGTTTCAATGGTCATAAACCCCCAGGTTCCTCTGA
  GCCCATCACAGTGAAGTTTGCAGCCAACCCCAACCAGAACAAAAACGTGGCACTCCTCTC
  GCAGCTGTACCACTCGCCAGCGCGACGGTTCGGAGGCCCCGTTCACCACCAGGCGCAGAG
  ATTCAGGTTCTCCCCCATGGGCGTCGATCACATGAGCGGGCTCTCTGGCGTCAACGTGCC
  AGGAAACGCCTCCTCCGGCTGGTGCATTTTCATCTACAACCTGGGGCAGGATGCCGACGA
  GGGGATCCTCTGGCAGATGTTTGGGCCGTTTGGTGCCGTCACCAATGTGAAAGTGATCCG
  CGACTTCAACACCAACAAGTGCAAAGGGTTTGGCTTTGTGACCATGACAAACTATGAAGA
  AGCCGCGATGGCCATAGCCAGCCTGAACGGCTACCGCCTGGGGGACAAAATCTTACAGGT
  TTCCTTCAAAACCAACAAGTCCCACAAATAACTCGCTCATGCTTTTTTTTGTACGGAATA
  GATAATTAAGAGTGAAGGAGTTGAAACTTTTCTTGTTAGTGTACAACTCATTTTGCGCCA
  ATTTTCACAAGTGTTTGTCTTTGTCTGAATGAGAAGTGAGAAGGTTTTTATACTCTGGGA
  TGCAACCGACATGTTCAAATGTTTGAAATCCCACAATGTTAGACCAATCTTAAGTTTCGT
  AAGTTATTTCCTTTAAGATATATATTAAACAGAAATCTAAGTAGAACTGCATTGACTAAC
  CAGTCCCTCTGGATGGTGGTGAACCTGAAGCATGCTTTAACCTCTAAGACTGTCTAACAC
  GCGTTTCATTCAATGTCTCCACAGACTGGGTAGCAAAAAAATCACCTTTTAGTTTTAGTT
  TTTAATCTAAAGATGTTAGACAGATGCTGAGTGTGCGTTTTCTCAACCGCTTCAACATTG
  TAAGCGATGTATGCTTTGGTTGACAGGAAGTTCCTTTTCCAGGCAGGTCCCGTTGCCACC
  TCCTGCTCACTCAGTCCCGGGCTCTGCCGAGTGGTCCTGGGAATGGCGGCGGGCCCGTCC
  AGCGTGGGCCACCACTGGGGCCGGGGGCCACGGGCTGCATGCTGGGCGGGCCCTCCAGAG
  AAGGACACAAACGTGTTTCGTAAGCCCAGGCACCAATGGGAATGGACCAAAGAGTTTCAG
  GGAAACTCCAGTATATTCCAGAGTCAGATCTAAGCTCCAGGCACGCCTGAAGATGTGTTG
  CTACTCTGACATCCCGAGTTTCTGTCCACACATTGCATGCACAGCGCCCCACACATTGGA
  TACTGTTGTTCACGATAATTTCTCCCGTTTTCCAGAGCATTTAACATAGCTTGGAGGCGT
  AAAATGGCTCTGTATTTTAATAACACAGAAACATTTGAGCATTGTATTTCTCGCATCCCT
  TCTCGTGAGCGCTTAGACCTTTTTCTATTTTAGTCGGATTTTGTTTTGGAATTTTGCTTT
  TGTATGAACACTCAGCAGAAAAGTACTTACTTCTTGCCAGTTATCTATTAACCAAAACCT
  TTGATTTGTAGTTTTAAAGATTAACCCTCAAAGTTCTCTTCATAACTGCCTTGACATTTT
  GGGTTGTTCTGTTCTGTTAATTTTCTTTTGCTTTTTTGTGTTTTTTGTTTGTTTTTACTT
  TTGCATTTAAGACCATTAAATTTGATTTTGTTTTGCTCGAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_001419
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001419.2, NP_001410.2
• RefSeq Size: 6075 bp
• RefSeq ORF: 981 bp
• Locus ID: 1994
• UniProt ID: Q15717
• Cytogenetics: 19p13.2
• Domains: RRM
• Gene Summary: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]