NUP93 (NM_014669) Human Untagged Clone

SKU SC321665

NUP93 (untagged)-Human nucleoporin 93kDa (NUP93)

Product Data

• Type: Human Untagged Clone
• Target Symbol: NUP93
• Synonyms: NIC96
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014669.2 GACGGCTGTAGCACAAGGATCTGCATCTCCAATGGATACTGAGGGGTTTGGTGAGCTCCT; TCAGCAAGCTGAACAGCTTGCTGCTGAGACTGAGGGCATCTCAGAGCTTCCCCATGTGGA; ACGGAACTTACAGGAGATCCAGCAGGCGGGAGAGCGCCTGCGTTCCCGTACCCTAACACG; CACGTCCCAGGAGACGGCAGATGTCAAGGCGTCAGTTCTCCTCGGGTCTCGGGGACTTGA; CATATCCCACATCTCCCAGCGATTGGAGAGTCTGAGTGCAGCCACCACCTTTGAGCCTCT; TGAGCCTGTGAAGGACACTGACATTCAGGGCTTCCTGAAGAATGAGAAGGACAATGCCCT; GCTGTCTGCCATCGAAGAGTCCCGGAAGAGGACCTTCGGCATGGCTGAGGAGTACCATCG; GGAGTCAATGTTGGTTGAGTGGGAGCAAGTGAAACAGCGAATTCTGCACACACTGCTGGC; ATCAGGAGAAGACGCCCTTGACTTTACTCAAGAAAGCGAGCCAAGCTACATCAGTGATGT; GGGACCCCCTGGTCGAAGCTCTCTGGATAACATCGAGATGGCCTATGCGCGGCAAATTTA; TATCTATAATGAGAAAATTGTAAATGGACACCTGCAGCCTAACCTGGTGGACCTTTGTGC; TTCCGTCGCAGAGCTCGATGATAAGAGCATTTCCGACATGTGGACCATGGTAAAACAAAT; GACAGACGTGTTGTTGACACCGGCAACGGATGCCCTGAAGAACCGCAGCAGCGTGGAAGT; GCGCATGGAGTTTGTCAGGCAGGCCTTGGCGTACCTTGAGCAGAGTTATAAGAATTACAC; CCTTGTGACTGTCTTTGGAAATTTGCATCAGGCCCAGCTGGGCGGGGTGCCTGGGACTTA; CCAATTGGTTCGAAGTTTCCTGAACATTAAACTGCCAGCTCCCTTGCCTGGACTACAGGA; TGGAGAGGTGGAAGGCCATCCTGTGTGGGCGCTAATTTACTACTGCATGCGCTGTGGAGA; CCTGCTTGCCGCTTCACAGGTAGTTAATCGAGCCCAGCACCAGCTGGGAGAGTTTAAAAC; CTGGTTCCAGGAGTACATGAACAGCAAGGACAGAAGATTGTCCCCAGCTACGGAAAACAA; GCTCCGGCTGCATTACCGTAGGGCCCTCAGGAACAATACAGATCCCTACAAGCGGGCCGT; GTACTGTATCATTGGCAGATGTGACGTCACCGACAACCAGAGTGAAGTGGCGGACAAAAC; TGAGGATTACCTGTGGCTGAAGTTGAACCAAGTGTGTTTTGACGACGATGGCACCAGCTC; CCCACAAGACAGGCTCACTCTCTCACAGTTCCAGAAGCAGTTGTTGGAAGACTATGGCGA; GTCCCACTTTACGGTGAACCAGCAACCCTTCCTCTACTTCCAAGTCCTGTTCCTGACAGC; GCAGTTTGAAGCAGCAGTTGCCTTTCTTTTCCGCATGGAGCGGCTGCGCTGCCATGCTGT; CCATGTAGCACTGGTGCTGTTTGAGCTGAAGCTGCTTTTAAAGTCCTCTGGACAGAGGGC; TCAGCTCCTCAGCCACGAGCCTGGTGACCCTCCTTGCTTGCGGCGGCTGAACTTCGTGCG; GCTCCTCATGCTGTACACCCGGAAGTTTGAGTCCACGGACCCAAGGGAGGCCCTCCAGTA; CTTCTATTTCCTCAGGGATGAGAAAGATAGTCAAGGAGAAAACATGTTTCTGCGCTGTGT; GAGTGAGCTTGTGATTGAAAGCCGAGAGTTCGATATGATTCTTGGGAAACTAGAGAATGA; CGGAAGTAGAAAGCCTGGAGTCATAGATAAGTTTACTAGTGACACAAAGCCTATTATCAA; CAAAGTTGCTTCTGTGGCAGAAAATAAAGGACTGTTTGAAGAGGCAGCAAAGCTGTATGA; CCTTGCCAAGAATGCTGACAAGGTACTGGAGCTGATGAACAAACTGCTGAGCCCTGTCGT; CCCCCAGATCAGTGCCCCGCAATCCAACAAGGAGAGGCTGAAGAACATGGCACTCTCCAT; TGCCGAACGGTATAGGGCTCAAGGAATAAGCGCAAATAAATTTGTGGACTCCACGTTCTA; TCTTCTTTTGGACTTGATCACCTTTTTTGACGAGTATCATAGTGGTCATATTGATAGAGC; TTTTGATATCATTGAGCGCTTGAAGCTGGTGCCCCTGAATCAGGAAAGTGTGGAAGAGAG; AGTGGCTGCCTTCAGAAATTTCAGTGATGAAATCAGGCACAACCTCTCAGAAGTGCTTCT; TGCCACCATGAACATCTTGTTCACACAGTTTAAGAGGCTCAAGGGGACAAGTCCATCCTC; GTCATCCAGGCCCCAGCGAGTCATCGAGGACCGCGACTCTCAACTCCGAAGTCAAGCCCG; CACTCTGATTACCTTTGCTGGAATGATACCATACCGAACGTCTGGGGACACCAATGCGAG; GCTGGTGCAGATGGAGGTCCTCATGAATTAAGTGCCATGCTTTGTGGGAGTCTGGGTCGG; CACACTGTCAGTACATCAGGCACATGGGCCCACTAGGCTGGGGTTTCTGGTTTTGTTTCT; GTTGTGTTTTGTTTTGGTTTCTGTATTATGTATTTTTGTCAACGCCAATAAATTTCTTTG; ATTTGTAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_014669
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_014669.2, NP_055484.2
• RefSeq Size: 2674 bp
• RefSeq ORF: 2460 bp
• Locus ID: 9688
• UniProt ID: Q8N1F7
• Cytogenetics: 16q13
• Domains: NIC
• Summary: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene encodes a nucleoporin protein that localizes both to the basket of the pore and to the nuclear entry of the central gated channel of the pore. The encoded protein is a target of caspase cysteine proteases that play a central role in programmed cell death by apoptosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]; Transcript Variant: This variant (1) encodes the longer isoform (1).