ABCG2(ABCG2) (NM_004827) Human Untagged Clone

CAT#: SC320948

ABCG2 (untagged)-Human ATP-binding cassette, sub-family G (WHITE), member 2 (ABCG2)

USD 196.00


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Size
    • 10 ug

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Specifications

Product Data
Product Name ABCG2(ABCG2) (NM_004827) Human Untagged Clone
Symbol ABCG2
Synonyms ABC15; ABCP; BCRP; BCRP1; BMDP; CD338; CDw338; EST157481; GOUT1; MRX; MXR; MXR-1; MXR1; UAQTL1
Vector pCMV6-AC
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_004827.2 GTCAGCGCTGCCTGAGCTCGTCCCCTGGATGTCCGGGTCTCCCCAGGCGGCCACCCGCCG
GCTCCCATCGTGACCTCCAGCCGCAGCGCCTCCCACGCCGGCCGCCGCGCGAGGGGAGCG
CTCGGGCGCGCCGGGTGTGGTTGGGGGAAGGGGTTGTGCCGCGCGCGGGCTGCGTGCTGT
GCCCACTCAAAAGGTTCCGGGCGCGCAGGAGGGAAGAGGCAGTGCCCGCCACTCCCACTG
AGATTGAGAGACGCGGCAAGGAGGCAGCCTGTGGAGGAACTGGGTAGGATTTAGGAATGC
ACCGTGCACATGCTTGGTGGTCTTGTTAAGTGGAAACTGCTGCTTTAGAGTTTGTTTGGA
AGGTCCGGGTGACTCATCCCAACATTTACATCCTTAATTGTTAAAGCGCTGCCTCCGAGC
GCACGCATCCTGAGATCCTGAGCCTTTGGTTAAGACCGAGCTCTATTAAGCTGAAAAGAT
AAAAACTCTCCAGATGTCTTCCAGTAATGTCGAAGTTTTTATCCCAGTGTCACAAGGAAA
CACCAATGGCTTCCCCGCGACAGCTTCCAATGACCTGAAGGCATTTACTGAAGGAGCTGT
GTTAAGTTTTCATAACATCTGCTATCGAGTAAAACTGAAGAGTGGCTTTCTACCTTGTCG
AAAACCAGTTGAGAAAGAAATATTATCGAATATCAATGGGATCATGAAACCTGGTCTCAA
CGCCATCCTGGGACCCACAGGTGGAGGCAAATCTTCGTTATTAGATGTCTTAGCTGCAAG
GAAAGATCCAAGTGGATTATCTGGAGATGTTCTGATAAATGGAGCACCGCGACCTGCCAA
TTTCAAATGTAATTCAGGTTACGTGGTACAAGATGATGTTGTGATGGGCACTCTGACGGT
GAGAGAAAACTTACAGTTCTCAGCAGCTCTTCGGCTTGCAACAACTATGACGAATCATGA
AAAAAACGAACGGATTAACAGGGTCATTCAAGAGTTAGGTCTGGATAAAGTGGCAGACTC
CAAGGTTGGAACTCAGTTTATCCGTGGTGTGTCTGGAGGAGAAAGAAAAAGGACTAGTAT
AGGAATGGAGCTTATCACTGATCCTTCCATCTTGTTCTTGGATGAGCCTACAACTGGCTT
AGACTCAAGCACAGCAAATGCTGTCCTTTTGCTCCTGAAAAGGATGTCTAAGCAGGGACG
AACAATCATCTTCTCCATTCATCAGCCTCGATATTCCATCTTCAAGTTGTTTGATAGCCT
CACCTTATTGGCCTCAGGAAGACTTATGTTCCACGGGCCTGCTCAGGAGGCCTTGGGATA
CTTTGAATCAGCTGGTTATCACTGTGAGGCCTATAATAACCCTGCAGACTTCTTCTTGGA
CATCATTAATGGAGATTCCACTGCTGTGGCATTAAACAGAGAAGAAGACTTTAAAGCCAC
AGAGATCATAGAGCCTTCCAAGCAGGATAAGCCACTCATAGAAAAATTAGCGGAGATTTA
TGTCAACTCCTCCTTCTACAAAGAGACAAAAGCTGAATTACATCAACTTTCCGGGGGTGA
GAAGAAGAAGAAGATCACAGTCTTCAAGGAGATCAGCTACACCACCTCCTTCTGTCATCA
ACTCAGATGGGTTTCCAAGCGTTCATTCAAAAACTTGCTGGGTAATCCCCAGGCCTCTAT
AGCTCAGATCATTGTCACAGTCGTACTGGGACTGGTTATAGGTGCCATTTACTTTGGGCT
AAAAAATGATTCTACTGGAATCCAGAACAGAGCTGGGGTTCTCTTCTTCCTGACGACCAA
CCAGTGTTTCAGCAGTGTTTCAGCCGTGGAACTCTTTGTGGTAGAGAAGAAGCTCTTCAT
ACATGAATACATCAGCGGATACTACAGAGTGTCATCTTATTTCCTTGGAAAACTGTTATC
TGATTTATTACCCATGAGGATGTTACCAAGTATTATATTTACCTGTATAGTGTACTTCAT
GTTAGGATTGAAGCCAAAGGCAGATGCCTTCTTCGTTATGATGTTTACCCTTATGATGGT
GGCTTATTCAGCCAGTTCCATGGCACTGGCCATAGCAGCAGGTCAGAGTGTGGTTTCTGT
AGCAACACTTCTCATGACCATCTGTTTTGTGTTTATGATGATTTTTTCAGGTCTGTTGGT
CAATCTCACAACCATTGCATCTTGGCTGTCATGGCTTCAGTACTTCAGCATTCCACGATA
TGGATTTACGGCTTTGCAGCATAATGAATTTTTGGGACAAAACTTCTGCCCAGGACTCAA
TGCAACAGGAAACAATCCTTGTAACTATGCAACATGTACTGGCGAAGAATATTTGGTAAA
GCAGGGCATCGATCTCTCACCCTGGGGCTTGTGGAAGAATCACGTGGCCTTGGCTTGTAT
GATTGTTATTTTCCTCACAATTGCCTACCTGAAATTGTTATTTCTTAAAAAATATTCTTA
AATTTCCCCTTAATTCAGTATGATTTATCCTCACATAAAAAAGAAGCACTTTGATTGAAG
TATTCAAAAAAAAAAAAAAAAAAAAAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_004827.2 unedited
GCGATTGTATACGACTCCTATAGGGCGGCGCGGCAAATTCGGCACGAGGGTCAGCGCTGC
CTGAGCTCGTCCCCTGGATGTCCGGGTCTCCCCAGGCGGCCACCCGCCGGCTCCCATCGT
GACCTCCAGCCGCAGCGCCTCCCACGCCGGCCGCCGCGCGAGGGGAGCGCTCGGGCGCGC
CGGGTGTGGTTGGGGGAAGGGGTTGTGCCGCGCGCGGGCTGCGTGCTGTGCCCACTCAAA
AGGTTCCGGGCGCGCAGGAGGGAAGAGGCAGTGCCCGCCACTCCCACTGAGATTGAGAGA
CGCGGCAAGGAGGCAGCCTGTGGAGGAACTGGTTTGTATTTAGGAATGCACCGTGCACAT
GCTTGGTGGTCTTGTTAAGTGGAAACTGCTGCTTTAGAGTTTGTTTGGAAGGTCCGGGTG
ACTCATCCCAACATTTACATCCTTAATTGTTAAAGCGCTGCCTCCGAGCGCACGCATCCT
GAGATCCTGAGCCTTTGGTTAAGACCGAGCTCTATTAAGCTGAAAAGATAAAAACTCTCC
AGATGTCTTCCAGTAATGTCGAAGTTTTTATCCCAGTGTCACAAGGAAACACCAATGGCT
TCCCCGCGACAGCTTCCAATGACCTGAAGGCATTTACTGAAGGAGCTGTGTTAAGTTTTC
ATAACATCTGCTATCGAGTAAAACTGAAGAGTGGCTTTCTACCTTGTCGAAAACCAGTTG
AGAAAGAATATTATCGAATATCAATGGGATCATGAAACCTGGTCTCACGCCATCCTGGGA
CCCACAGTGGAGGCAGATCTTCGTTATTAGATGTCTTACTGCTAGAAGATCCAAGTGATT
ATTCTGAGAATGTTCTGAATAATGAGCACGCGACCTGCCCATTCAACTGTAATTCAAGTT
ACCTTGTACAGATGATGTGGAATTGACACTCTGGACGGTGGAGAGAAAAACTTACAGTTT
CTCAGACA
Restriction Sites Please inquire     
Tag Tag Free
ACCN NM_004827
ORF Size 1968 bp
Insert Size 2500
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_004827.2, NP_004818
RefSeq Size 4445
Locus ID 9429
Cytogenetics 4q22.1
Domains ABC_tran, AAA
Protein Families ES Cell Differentiation/IPS, Transmembrane, Druggable Genome
Protein Pathways ABC transporters
Gene Summary The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations