SNX1 (NM_003099) Human Untagged Clone

CAT#: SC320230

SNX1 (untagged)-Human sorting nexin 1 (SNX1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SNX1
• Synonyms: HsT17379; VPS5
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003099.3 GTGGAAGAAGATGGCGTCGGGTGGTGGTGGCTGTAGCGCTTCGGAGAGACTGCCTCCGCC
  CTTCCCCGGCCTGGAGCCGGAGTCCGAGGGGGCGGCCGGGGGATCAGAACCCGAGGCTGG
  GGACAGCGACACCGAGGGGGAGGACATTTTCACCGGCGCCGCGGTGGTCAGTAAACATCA
  GTCTCCAAAGATAACTACATCCCTTCTTCCCATCAACAATGGCTCCAAAGAAAATGGGAT
  CCATGAAGAACAAGACCAAGAGCCACAGGATCTCTTTGCAGATGCCACAGTGGAGCTATC
  CTTGGACAGCACACAAAATAATCAGAAGAAGGTGCTAGCCAAAACACTCATTTCTCTTCC
  TCCTCAGGAAGCCACAAATTCTTCGAAGCCCCAGCCAACCTATGAGGAGCTAGAGGAAGA
  AGAACAGGAGGATCAATTTGATTTGACAGTCGGTATAACTGATCCTGAGAAGATAGGGGA
  TGGTATGAATGCATATGTAGCCTACAAAGTTACAACACAGACAAGCTTACCATTGTTCAG
  AAGCAAACAGTTTGCAGTAAAAAGAAGATTTAGTGACTTTCTGGGTCTTTATGAGAAGCT
  TTCCGAGAAGCACTCTCAGAATGGCTTCATTGTCCCTCCACCCCCGGAGAAGAGCCTCAT
  AGGGATGACAAAAGTGAAAGTTGGGAAGGAAGATTCTTCTTCTGCAGAATTTCTTGAAAA
  ACGGAGGGCCGCTTTAGAAAGGTACCTTCAGAGGATTGTAAATCATCCTACCATGTTACA
  GGACCCTGACGTCAGAGAGTTCTTGGAAAAAGAAGAGCTGCCACGTGCCGTGGGTACCCA
  GACATTGAGTGGTGCTGGTCTCCTCAAGATGTTCAACAAAGCCACAGATGCCGTCAGCAA
  AATGACCATCAAGATGAATGAATCAGACATTTGGTTTGAGGAGAAGCTCCAGGAGGTAGA
  GTGTGAGGAGCAGCGCTTACGGAAACTGCATGCTGTTGTAGAAACTCTAGTCAACCATAG
  GAAAGAGCTAGCGCTGAACACAGCCCAGTTTGCAAAGAGTCTAGCCATGCTTGGGAGCTC
  TGAGGACAACACGGCATTGTCACGGGCACTCTCCCAGCTGGCTGAGGTGGAAGAAAAAAT
  TGAGCAGCTCCACCAGGAACAGGCCAACAATGACTTCTTCCTCCTTGCTGAGCTCCTGAG
  TGACTACATTCGCCTCCTGGCCATAGTCCGCGCTGCCTTCGACCAGCGCATGAAGACATG
  GCAGCGCTGGCAGGATGCCCAAGCCACACTGCAGAAGAAGCGGGAGGCCGAGGCTCGGCT
  GCTGTGGGCCAACAAGCCTGATAAGCTGCAGCAGGCCAAGGACGAGATCCTCGAGTGGGA
  GTCTCGGGTGACTCAATATGAAAGGGACTTCGAGAGGATTTCAACAGTGGTCCGAAAAGA
  AGTGATACGGTTTGAGAAAGAGAAATCCAAGGACTTCAAGAACCACGTGATCAAGTACCT
  TGAGACACTCCTTTACTCACAGCAGCAGCTGGCAAAGTACTGGGAAGCCTTCCTTCCTGA
  GGCAAAGGCCATCTCCTAATGGACCAAGGACCCCAGAGCCCACCTGTGTGACGCTGCCTT
  TTTATACACTGTCCTCCTCCACCTTGATGGACCCCTAGTGATGCATCCTGCCTAGGCTGG
  ACTTAACCCCTTCCTCCCTGTCCCCACGACCAACTGTCCCCAGTTACTCTAACCGTTATT
  TCATTTAGCTTCCATATATATTTTCTTACCTAAGAGAATAGTTTCCTGCTTTAAGCAAAA
  GACCTACAATAGGTGGTGGAATTATGGGATGGGGTGGAGTATTGATATAAATATATAAAT
  ACAAATGTATATTTTTCAGGATGTGGTTTAGGAACTGGGAATAACGTTTTCTGTTACTCC
  TGATGGTGCCATGAAAAGGTTATGTAATAAAATATTTTAAAATCAAAAAAAAAAAAAAAA
  AA
• Restriction Sites: Please inquire
• ACCN: NM_003099
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003099.3, NP_003090.2
• RefSeq Size: 8221 bp
• RefSeq ORF: 1569 bp
• Locus ID: 6642
• UniProt ID: Q13596
• Cytogenetics: 15q22.31
• Domains: PX, Sorting_nexin
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.