STAC (NM_003149) Human Untagged Clone

CAT#: SC319517

STAC (untagged)-Human SH3 and cysteine rich domain (STAC)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STAC
• Synonyms: STAC1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003149.1 GAGGCTGGAGGAGGGCACGTCGGCGCCTCGGCGAGGATGGGAGTCCCCAGGACCCGGAGC
  TGAGCAGCCTGGCGCGCGGCGGGCAGGGCGCGCAGGACAGAAGCCTCGCTGTTCCTCCGG
  GAGCCCAACACCGTTCCCGCGCGGCCACGATGATCCCTCCGAGCAGCCCCCGCGAGGACG
  GCGTGGACGGGCTGCCCAAGGAGGCGGTGGGCGCCGAGCAACCGCCCTCTCCTGCATCCA
  CCAGCAGCCAGGAATCCAAGCTCCAGAAACTAAAACGATCACTTTCTTTCAAGACCAAGA
  GTTTACGGAGCAAAAGTGCTGACAACTTCTTCCAGCGAACCAACAGCGAAGACATGAAAC
  TGCAAGCACACATGGTGGCTGAGATCAGCCCCAGCTCCAGCCCACTCCCTGCTCCAGGAA
  GCCTGACGTCCACACCCGCCAGGGCTGGTCTGCATCCAGGTGGCAAGGCTCATGCCTTTC
  ATGAATACATCTTCAAGAAGCCCACTTTCTGTGATGTCTGCAACCACATGATAGTGGGAA
  CAAATGCTAAGCATGGACTGCGCTGCAAAGCCTGTAAGATGAGCATCCACCACAAGTGCA
  CAGATGGCCTGGCACCCCAGCGGTGCATGGGCAAGCTGCCAAAGGGGTTTCGGCGTTACT
  ACAGCTCCCCCTTGCTCATTCATGAACAGTTTGGCTGCATTAAAGAAGTTATGCCCATTG
  CCTGTGGCAATAAGGTGGACCCTGTCTACGAGACCCTCCGCTTCGGCACCTCCCTGGCCC
  AGAGGACAAAGAAGGGCAGCTCCGGCAGTGGCTCTGACTCACCTCACAGAACCTCTACTT
  CAGATCTTGTGGAGGTTCCTGAGGAAGCCAATGGGCCAGGAGGCGGGTATGACCTAAGGA
  AACGCAGCAACAGCGTGTTTACATATCCAGAAAATGGCACTGATGATTTCAGAGATCCAG
  CGAAGAACATAAACCACCAGGGATCTCTTTCCAAAGACCCATTACAGATGAACACCTATG
  TTGCCTTGTACAAATTTGTACCACAGGAGAATGAAGATTTGGAAATGAGGCCAGGAGACA
  TAATTACTCTTTTAGAGGATTCCAATGAAGACTGGTGGAAAGGGAAAATTCAAGACAGAA
  TTGGCTTCTTTCCAGCCAACTTTGTTCAGAGACTACAACAAAATGAGAAGATTTTTAGAT
  GTGTTAGAACCTTCATTGGGTGTAAGGAACAGGGGCAGATAACACTGAAAGAGAATCAGA
  TCTGCGTGAGTTCTGAAGAAGAACAAGATGGTTTTATCAGAGTCCTCAGTGGAAAAAAGA
  AAGGCCTCATCCCCCTTGATGTACTAGAAAACATCTGATTGCTGGCTCCTCCTCCGTTTG
  CAGTAGGCAAGCTCTGCTGCGATGCCTCTGCCTCATCTCACACTGCGTCAACCCAAAGGA
  GCTGCCGCACTGACCCAGCCCCCCAGGAAACAGTGAGACAAGAATCAAGTATCTGAGACT
  GTGGAGTAATAGCCACAAAACAGAGGGCCCACTGCACAGCATATCCAGGCTGCCACAGGT
  GGGGACGAGGCTGAGAGAGTCAGCAGGCAGAGCCAGATGCCATGCTTGGCAGCAGCAGTA
  GGACTATAAACCACAGCTGTCCCCCAGGATCCCACTCCTTTCCTGTCTGTGTGGTGTAAG
  TTAACACACTGGAGTGTGCTCCAGTTTGCAGGGTAGCCCAGTGCAAGGTTCAGATCCATG
  TAGCTAAGTATTATCCTGCTTCCAGACCTATGTCACCAGTACCAATCAGTCAGTGTCATC
  ACATTTCAGGCCCCAAGCAATCTCTGTGCAAAGCATCAGAAAGACCTGCTTCCCAGCCCC
  CAGCATTCCAGTGCTCTCCAGGCTTCCTCTCTTTGTGATTGTGCTGTCCAGAGTGTCCAG
  CTTGTTCTTTCTTTCTCTTCAGTCCTCTGAGTACATCTGGTGGTGTGCATTAGATGTGAG
  GGCTATGTTGACATGGCATCACCTCCAAAGACCTGACCTGCCTAAAGACTGATGACAGGC
  CATCCTTCCTGCTGTTCTAGGTACTGGCCTGGGTGACAGAGCAGGACATGAGACATAGAT
  ACAGTGGGGAGGAGAAGTGGGGAAAGGTGGAGCAGAGAGTTCTTACTTATTGAAGATTAT
  ACAGCCCTTTCGGTTATGAAGTCCCTGCTTGAAGGCAATGGACCTGGGGAAGAGACTATC
  ACAAAAAGTCTCCATTTTCATTTTACATCCTCTCTATTGGAGGCAGCACTTTTCCCTCAT
  GCTGTCCTATAGGACTCCACTTTGAAGGTTGTGCCTACGTTGCAGGGAACTAGGAACATG
  GAGGGGAACCAACAACAGCATCTTAGAAGAAATGTAGCCAAATTGGAGTCCATTCTTCTT
  TAGGGCAGTATATGAAATCCTAGCAGATGTAAAATGGAAAAGAATCCTAATGCTTCTTCC
  TTCAGAAAGTAGAGGAACTAGGGGCCCAATTAGCATCATCTAGGGGAATCTCTATTACTC
  TGTACTTATACTAATGTTTACAAGAATGCAATATACTGTGATGCCTTCCTACTCAAGCCT
  CCTAGCATTCAAACTTCCATCCTATTAGTCATTAACATGGTTAAACTTCAATTCACAATC
  ACCTTGGAATCAATGTCAGTTTGATTTATTTTGTTACAGAGCAATAAAATCATTAGAACA
  ATGAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_003149
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003149.1, NP_003140.1
• RefSeq Size: 2963 bp
• RefSeq ORF: 1209 bp
• Locus ID: 6769
• UniProt ID: Q99469
• Cytogenetics: 3p22.3-p22.2
• Domains: SH3, DAG_PE-bind
• Gene Summary: Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity. Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1).