MSF (SEPT9) (NM_001113492) Human Untagged Clone

CAT#: SC318870

41526 (untagged)-Human septin 9 (SEPT9), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEPTIN9
• Synonyms: AF17q25; MSF; MSF1; NAPB; PNUTL4; SEPT9; SeptD1; SINT1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001113492, the custom clone sequence may differ by one or more nucleotides
  ATGGAGCCCCCTGCCTCCAAGGTCCCCGAGGTGCCCACTGCCCCTGCCACCGACGCAGCC
  CCCAAGAGGGTGGAGATCCAGATGCCCAAGCCTGCTGAGGCGCCCACCGCCCCCAGCCCA
  GCCCAGACCTTGGAGAATTCAGAGCCTGCCCCTGTGTCTCAGCTGCAGAGCAGGCTGGAG
  CCCAAGCCCCAGCCCCCTGTGGCTGAGGCTACACCCCGGAGCCAGGAGGCCACTGAGGCG
  GCTCCCAGCTGCGTTGGCGACATGGCCGACACCCCCAGAGATGCCGGGCTCAAGCAGGCG
  CCTGCATCACGGAACGAGAAGGCCCCGGTGGACTTCGGCTACGTGGGGATTGACTCCATC
  CTGGAGCAGATGCGCCGGAAGGCCATGAAGCAGGGCTTCGAGTTCAACATCATGGTGGTC
  GGGCAGAGCGGCTTGGGTAAATCCACCTTAATCAACACCCTCTTCAAATCCAAAATCAGC
  CGGAAGTCGGTGCAGCCCACCTCAGAGGAGCGCATCCCCAAGACCATCGAGATCAAGTCC
  ATCACGCACGATATTGAGGAGAAAGGCGTCCGGATGAAGCTGACAGTGATTGACACACCA
  GGGTTCGGGGACCACATCAACAACGAGAACTGCTGGCAGCCCATCATGAAGTTCATCAAT
  GACCAGTACGAGAAATACCTGCAGGAGGAGGTCAACATCAACCGCAAGAAGCGCATCCCG
  GACACCCGCGTCCACTGCTGCCTCTACTTCATCCCCGCCACCGGCCACTCCCTCAGGCCC
  CTGGACATCGAGTTTATGAAACGCCTGAGCAAGGTGGTCAACATCGTCCCTGTCATCGCC
  AAGGCGGACACACTCACCCTGGAGGAGAGGGTCCACTTCAAACAGCGGATCACCGCAGAC
  CTGCTGTCCAACGGCATCGACGTGTACCCCCAGAAGGAATTTGATGAGGACTCGGAGGAC
  CGGCTGGTGAACGAGAAGTTCCGGGAGATGATCCCATTTGCTGTGGTGGGCAGTGACCAC
  GAGTACCAGGTCAACGGCAAGAGGATCCTTGGGAGGAAGACCAAGTGGGGTACCATCGAA
  GTTGAAAACACCACACACTGTGAGTTTGCCTACCTGCGGGACCTTCTCATCAGGACGCAC
  ATGCAGAACATCAAGGACATCACCAGCAGCATCCACTTCGAGGCGTACCGTGTGAAGCGC
  CTCAACGAGGGCAGCAGCGCCATGGCCAACGGCATGGAGGAGAAGGAGCCAGAAGCCCCG
  GAGATG
  
• Restriction Sites: Please inquire
• ACCN: NM_001113492
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001113492.1, NP_001106964.1
• RefSeq Size: 4012 bp
• RefSeq ORF: 1269 bp
• Locus ID: 10801
• UniProt ID: Q9UHD8
• Cytogenetics: 17q25.3
• Protein Families: Druggable Genome
• Gene Summary: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (5, also known as zeta or v4*) lacks the first 5' exon, but has an alternate 5' exon, which results in a downstream AUG start codon, as compared to variant 1. The resulting isoform (e) has a shorter N-terminus, as compared to isoform a.