Septin 8 (SEPT8) (NM_001098812) Human Untagged Clone

CAT#: SC316522

41525 (untagged)-Human septin 8 (SEPT8), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEPTIN8
• Synonyms: SEP2; SEPT8
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001098812, the custom clone sequence may differ by one or more nucleotides
  ATGGCGGCCACCGACCTGGAGCGCTTCTCGAATGCAGAGCCAGAGCCCCGGAGCCTCTCC
  CTGGGCGGCCATGTGGGTTTCGACAGCCTCCCCGACCAGCTGGTCAGCAAGTCGGTCACT
  CAGGGCTTCAGCTTCAACATCCTCTGTGTGGGGGAGACCGGCATTGGCAAATCCACACTG
  ATGAACACACTCTTCAACACGACCTTCGAGACTGAGGAAGCCAGTCACCATGAGGCATGC
  GTGCGCCTGCGGCCCCAGACCTATGACCTCCAGGAGAGCAACGTGCAGCTCAAGCTGACC
  ATTGTGGATGCCGTGGGCTTTGGGGATCAGATCAATAAGGATGAGAGTTACAGGCCCATA
  GTTGACTACATCGATGCGCAGTTTGAAAATTATCTGCAGGAGGAGCTGAAGATCCGCCGC
  TCGCTCTTCGACTACCATGACACAAGGATCCACGTTTGCCTCTACTTCATCACGCCCACA
  GGGCACTCCCTGAAGTCTCTAGATCTAGTGACCATGAAGAAACTAGACAGCAAGGTGAAC
  ATTATTCCCATCATCGCCAAGGCTGACACCATCTCCAAGAGCGAGCTCCACAAGTTCAAG
  ATCAAGATCATGGGCGAGTTGGTCAGCAACGGGGTCCAGATCTACCAGTTCCCCACGGAT
  GATGAGGCTGTTGCAGAGATTAACGCAGTCATGAATGCACATCTGCCCTTTGCCGTGGTG
  GGCAGCACCGAGGAGGTGAAGGTGGGGAACAAGCTGGTCCGAGCACGGCAGTACCCCTGG
  GGAGTGGTGCAGGTGGAGAATGAGAATCACTGCGACTTCGTGAAGCTGCGGGAGATGTTG
  ATCCGGGTGAACATGGAAGACCTCCGCGAGCAGACCCACAGCCGGCACTACGAGCTCTAC
  CGGCGCTGCAAGTTGGAGGAGATGGGCTTTCAGGACAGCGATGGTGACAGCCAGCCCTTC
  AGCCTACAAGAGACATACGAGGCCAAGAGGAAGGAGTTCCTAAGTGAGCTGCAGAGGAAG
  GAGGAAGAGATGAGGCAGATGTTTGTCAACAAAGTGAAGGAGACAGAGCTGGAGCTGAAG
  GAGAAGGAAAGGGAGCTCCATGAGAAGTTTGAGCACCTGAAGCGGGTCCACCAGGAGGAG
  AAGCGCAAGGTGGAGGAAAAGCGCCGGGAACTGGAGGAGGAGACCAACGCCTTCAATCGC
  CGGAAGGCTGCGGTGGAGGCCCTGCAGTCGCAGGCCTTGCACGCCACCTCGCAGCAGCCC
  CTGAGGAAGGACAAGGACAAGAAGAAAGCCAGTGGCTGGTCTTCCATTTACAGTGTCACT
  ATTCCC
  
• Restriction Sites: Please inquire
• ACCN: NM_001098812
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001098812.1, NP_001092282.1
• RefSeq Size: 4076 bp
• RefSeq ORF: 1329 bp
• Locus ID: 23176
• UniProt ID: Q92599
• Cytogenetics: 5q31.1
• Gene Summary: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (3) differs in the 3' UTR and 3' coding region compared to variant 1. The resulting isoform (c) is shorter and has a distinct C-terminus compared to isoform a.