SOS2 (NM_006939) Human Untagged Clone

CAT#: SC315360

SOS2 (untagged)-Human son of sevenless homolog 2 (Drosophila) (SOS2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SOS2
• Synonyms: NS9; SOS-2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006939 edited
  ATGCAGCAGGCGCCGCAGCCTTACGAGTTCTTCAGCGAGGAGAACAGTCCGAAATGGCGG
  GGACTGTTGGTCTCGGCCCTGCGGAAGGTTCAGGAACAAGTGCATCCCACTCTCTCAGCT
  AATGAAGAGTCTCTCTATTATATTGAAGAGCTGATTTTTCAGCTGCTTAATAAATTATGC
  ATGGCCCAGCCAAGGACTGTTCAAGATGTAGAGGAGCGAGTTCAGAAGACCTTTCCTCAC
  CCAATTGATAAATGGGCCATTGCTGATGCACAATCTGCTATAGAAAAACGAAAACGAAGA
  AATCCTCTTTTACTGCCTGTGGACAAAATCCATCCTTCGTTGAAGGAAGTATTAGGGTAC
  AAAGTGGACTACCATGTATCCCTATATATTGTGGCTGTACTAGAGTATATCTCAGCTGAT
  ATTTTAAAATTGGCTGGTAATTATGTTTTTAATATCCGGCATTATGAAATATCTCAGCAG
  GACATTAAAGTGTCAATGTGTGCGGATAAGGTTTTGATGGACATGTTTGATCAGGATGAC
  ATAGGTTTGGTTTCTCTCTGTGAAGATGAACCTAGTTCTTCTGGTGAATTAAACTACTAT
  GATCTTGTCAGAACTGAAATCGCAGAAGAAAGACAGTATCTACGGGAATTAAATATGATC
  ATAAAAGTGTTTCGAGAAGCCTTTCTTTCTGATAGAAAGCTGTTTAAACCTTCTGATATC
  GAAAAGATTTTTAGTAACATTTCAGATATACATGAATTGACTGTGAAACTTTTAGGTTTG
  ATTGAAGACACAGTTGAAATGACTGATGAAAGCAGTCCTCATCCCTTAGCTGGCAGCTGT
  TTTGAAGATTTGGCAGAAGAGCAAGCATTTGATCCTTATGAAACATTATCACAGGACATT
  CTTTCACCAGAGTTTCATGAACATTTCAATAAATTGATGGCCAGACCTGCAGTTGCTCTA
  CACTTTCAGTCCATTGCTGATGGTTTTAAAGAGGCAGTTCGTTATGTCCTTCCACGTCTT
  ATGCTGGTGCCAGTGTATCACTGTTGGCACTACTTTGAGTTACTAAAGCAATTGAAAGCA
  TGTAGTGAAGAACAAGAAGACAGAGAATGTTTGAACCAAGCTATTACTGCTCTCATGAAT
  CTCCAAGGTAGCATGGACCGAATTTACAAGCAGTATTCACCTAGACGTCGACCTGGAGAT
  CCTGTTTGCCCTTTTTATAGTCACCAATTAAGAAGCAAACACCTGGCTATCAAAAAAATG
  AATGAAATTCAGAAAAATATCGATGGATGGGAAGGCAAAGATATTGGACAGTGTTGTAAT
  GAATTCATTATGGAGGGACCATTGACAAGAATCGGTGCCAAACATGAACGGCATATTTTT
  CTGTTTGATGGCTTAATGATCAGTTGTAAACCTAATCATGGCCAGACTCGGCTTCCAGGT
  TACAGTAGTGCAGAATACAGGTTAAAAGAAAAATTTGTCATGAGGAAAATACAAATTTGT
  GATAAAGAAGATACTTGTGAGCACAAGCATGCATTTGAATTAGTATCCAAAGATGAGAAC
  AGCATAATATTTGCTGCTAAGTCTGCTGAAGAAAAAAACAACTGGATGGCAGCCCTTATT
  TCTCTTCATTATCGTAGTACTCTAGATCGAATGTTAGATTCAGTATTATTGAAAGAAGAA
  AATGAGCAACCACTGAGATTACCAAGTCCTGAAGTATATCGTTTTGTAGTAAAAGACTCT
  GAGGAAAACATTGTTTTTGAAGACAACTTGCAAAGTAGAAGTGGCATCCCCATTATTAAA
  GGAGGAACTGTAGTGAAATTAATTGAAAGGTTAACATATCATATGTATGCAGATCCCAAT
  TTTGTTCGTACTTTTCTTACCACATATCGTTCATTTTGTAAACCACAGGAATTGCTGAGC
  TTACTGATTGAACGGTTTGAAATTCCAGAGCCAGAACCTACTGACGCAGACAAATTGGCA
  ATAGAGAAAGGCGAGCAGCCAATCAGTGCAGACCTTAAAAGATTTCGCAAGGAATATGTC
  CAACCAGTACAACTTAGGATCTTAAATGTATTTCGGCATTGGGTTGAACATCATTTTTAT
  GACTTTGAAAGAGACTTGGAATTGCTTGAAAGACTAGAATCCTTCATTTCAAGTGTAAGA
  GGGAAAGCTATGAAAAAATGGGTAGAGTCAATTGCTAAGATCATCAGGAGGAAGAAGCAA
  GCTCAGGCAAACGGAGTAAGCCATAATATTACCTTTGAAAGTCCACCTCCACCAATTGAA
  TGGCATATCAGCAAACCAGGACAGTTTGAAACATTTGATCTCATGACACTTCATCCAATA
  GAAATTGCACGTCAGCTGACACTTTTGGAGTCTGATCTTTACAGGAAAGTTCAACCGTCT
  GAACTTGTAGGGAGTGTGTGGACCAAAGAAGATAAAGAAATAAATTCTCCAAATTTATTA
  AAAATGATTCGCCATACCACAAATCTCACCCTCTGGTTTGAAAAATGCATTGTGGAAGCA
  GAAAATTTTGAAGAACGGGTGGCAGTACTAAGTAGAATTATAGAAATTCTGCAAGTTTTT
  CAAGATTTGAATAATTTCAATGGCGTATTGGAGATAGTCAGTGCAGTAAATTCAGTGTCA
  GTATACAGACTAGACCATACCTTTGAGGCACTGCAGGAAAGGAAAAGGAAAATTTTGGAC
  GAAGCTGTGGAATTAAGTCAAGATCACTTTAAAAAATACCTAGTAAAACTTAAGTCAATC
  AATCCACCTTGTGTGCCTTTTTTTGGAATATATTTAACAAATATTCTGAAGACCGAAGAA
  GGGAATAATGATTTTTTAAAAAAGAAAGGGAAAGATTTAATCAATTTCAGTAAGAGGAGG
  AAAGTAGCTGAAATTACTGGAGAAATTCAGCAGTATCAGAATCAGCCTTACTGTTTACGG
  ATAGAACCAGATATGAGGAGATTCTTTGAAAACCTTAACCCCATGGGAAGTGCATCTGAA
  AAAGAGTTTACAGATTATTTGTTCAACAAGTCACTAGAAATTGAACCTCGAAACTGCAAA
  CAGCCACCTCGATTTCCTAGGAAATCAACTTTTTCCTTAAAATCTCCTGGAATAAGGCCT
  AACACAGGCCGACATGGCTCTACCTCAGGTACTTTACGAGGTCACCCAACACCATTAGAA
  AGAGAACCATGTAAAATAAGCTTTAGTCGGATTGCTGAAACTGAGCTGGAATCAACAGTG
  TCAGCACCAACCTCTCCAAATACACCATCTACTCCACCAGTATCTGCTTCTTCAGACCTT
  AGTGTATTTTTAGATGTGGATCTCAACAGCTCCTGTGGCAGCAATAGCATCTTTGCTCCA
  GTGCTTTTGCCACATTCAAAGTCTTTCTTTAGTTCATGTGGTAGTTTACATAAACTAAGT
  GAAGAGCCCCTGATTCCTCCTCCTCTTCCTCCTCGAAAAAAGTTTGATCATGATGCTTCA
  AATTCCAAGGGAAATATGAAATCTGATGATGATCCTCCTGCTATTCCACCGAGACAGCCT
  CCTCCTCCAAAGGTAAAACCCAGAGTTCCTGTTCCTACTGGTGCATTTGATGGGCCTCTG
  CATAGTCCACCTCCGCCACCACCAAGAGATCCTCTTCCTGATACCCCTCCACCAGTTCCC
  CTTCGGCCTCCAGAACACTTTATAAACTGTCCATTTAATCTTCAGCCACCTCCACTGGGG
  CATCTTCACAGAGATTCAGACTGGCTCAGAGACATTAGTACGTGTCCAAATTCGCCAAGC
  ACTCCTCCTAGCACACCCTCTCCAAGGGTACCGCGTCGATGCTATGTGCTCAGTTCTAGT
  CAGAATAATCTTGCTCATCCTCCAGCTCCCCCTGTTCCACCAAGGCAGAATTCAAGCCCT
  CATCTGCCAAAACTGCCACCAAAGACTTACAAACGGGAGCTTTCGCACCCCCCATTGTAC
  AGACTGCCTTTGCTAGAAAATGCAGAAACTCCCCAATGA
  
• Restriction Sites: Please inquire
• ACCN: NM_006939
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006939.1, NP_008870.1
• RefSeq Size: 3999 bp
• RefSeq ORF: 3999 bp
• Locus ID: 6655
• UniProt ID: Q07890
• Cytogenetics: 14q21.3
• Protein Pathways: Acute myeloid leukemia, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Dorso-ventral axis formation, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway
• Gene Summary: This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016]