LRIG1 (NM_015541) Human Untagged Clone

CAT#: SC315173

LRIG1 (untagged)-Human leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LRIG1
• Synonyms: LIG-1; LIG1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015541 edited
  ATGGCGCGGCCGGTCCGGGGAGGGCTCGGGGCCCCGCGCCGCTCGCCTTGCCTTCTCCTT
  CTCTGGCTGCTTTTGCTTCGGCTGGAGCCGGTGACCGCCGCGGCCGGCCCGCGGGCGCCC
  TGCGCGGCCGCCTGCACTTGCGCTGGGGACTCGCTGGACTGCGGTGGGCGCGGGCTGGCT
  GCGTTGCCCGGGGACCTGCCCTCCTGGACGCGGAGCCTAAACCTGAGTTACAACAAACTC
  TCTGAGATTGACCCTGCTGGTTTTGAGGACTTGCCGAACCTACAGGAAGTGTACCTCAAT
  AATAATGAGTTGACAGCGGTACCATCCCTGGGCGCTGCTTCATCACATGTCGTCTCTCTC
  TTTCTGCAGCACAACAAGATTCGCAGCGTGGAGGGGAGCCAGCTGAAGGCCTACCTTTCC
  TTAGAAGTGTTAGATCTGAGTTTGAACAACATCACGGAAGTGCGGAACACCTGCTTTCCA
  CACGGACCGCCTATAAAGGAGCTCAACCTGGCAGGCAATCGGATTGGCACCCTGGAGTTG
  GGAGCATTTGATGGTCTGTCACGGTCGCTGCTAACTCTTCGCCTGAGCAAAAACAGGATC
  ACCCAGCTTCCTGTAAGAGCATTCAAGCTACCCAGGCTGACACAACTGGACCTCAATCGG
  AACAGGATTCGGCTGATAGAGGGCCTCACCTTCCAGGGGCTCAACAGCTTGGAGGTGCTG
  AAGCTTCAGCGAAACAACATCAGCAAACTGACAGATGGGGCCTTCTGGGGACTGTCCAAG
  ATGCATGTGCTGCACCTGGAGTACAACAGCCTGGTAGAAGTGAACAGCGGCTCGCTCTAC
  GGCCTCACGGCCCTGCATCAGCTCCACCTCAGCAACAATTCCATCGCTCGCATTCACCGC
  AAGGGCTGGAGCTTCTGCCAGAAGCTGCATGAGTTGGTCCTGTCCTTCAACAACCTGACA
  CGGCTGGACGAGGAGAGCCTGGCCGAGCTGAGCAGCCTGAGTGTCCTGCGTCTCAGCCAC
  AATTCCATCAGCCACATTGCGGAGGGTGCCTTCAAGGGACTCAGGAGCCTGCGAGTCTTG
  GATCTGGACCATAACGAGATTTCGGGCACAATAGAGGACACGAGCGGCGCCTTCTCAGGG
  CTCGACAGCCTCAGCAAGCTGACTCTGTTTGGAAACAAGATCAAGTCTGTGGCTAAGAGA
  GCATTCTCGGGGCTGGAAGGCCTGGAGCACCTGAACCTTGGAGGGAATGCGATCAGATCT
  GTCCAGTTTGATGCCTTTGTGAAGATGAAGAATCTTAAAGAGCTCCATATCAGCAGCGAC
  AGCTTCCTGTGTGACTGCCAGCTGAAGTGGCTGCCCCCGTGGCTAATTGGCAGGATGCTG
  CAGGCCTTTGTGACAGCCACCTGTGCCCACCCAGAATCACTGAAGGGTCAGAGCATTTTC
  TCTGTGCCACCAGAGAGTTTCGTGTGCGATGACTTCCTGAAGCCACAGATCATCACCCAG
  CCAGAAACCACCATGGCTATGGTGGGCAAGGACATCCGGTTTACATGCTCAGCAGCCAGC
  AGCAGCAGCTCCCCCATGACCTTTGCCTGGAAGAAAGACAATGAAGTCCTGACCAATGCA
  GACATGGAGAACTTTGTCCACGTCCACGCGCAGGACGGGGAAGTGATGGAGTACACCACC
  ATCCTGCACCTCCGTCAGGTCACTTTCGGGCACGAGGGCCGCTACCAATGTGTCATCACC
  AACCACTTTGGCTCCACCTATTCACATAAGGCCAGGCTCACCGTGAATGTGTTGCCATCA
  TTCACCAAAACGCCCCACGACATAACCATCCGGACCACCACCATGGCCCGCCTCGAATGT
  GCTGCCACAGGTCACCCAAACCCTCAGATTGCCTGGCAGAAGGATGGAGGCACGGATTTC
  CCCGCTGCCCGTGAGCGACGCATGCATGTCATGCCGGATGACGACGTGTTTTTCATCACT
  GATGTGAAAATAGATGACGCAGGGGTTTACAGCTGTACTGCTCAGAACTCAGCCGGTTCT
  ATTTCAGCTAATGCCACCCTGACTGTCCTAGAGACCCCATCCTTGGTGGTCCCCTTGGAA
  GACCGTGTGGTATCTGTGGGAGAAACAGTGGCCCTCCAATGCAAAGCCACGGGGAACCCT
  CCGCCCCGCATCACCTGGTTCAAGGGGGACCGCCCGCTGAGCCTCACTGAGCGGCACCAC
  TTGACCCCTGACAACCAGCTCCTGGTGGTTCAGAACGTGGTGGCAGAGGATGCGGGCCGA
  TATACCTGTGAGATGTCCAACACCCTGGGCACGGAGCGAGCTCACAGCCAGCTGAGCGTC
  CTGCCCGCAGCAGGCTGCAGGAAGGATGGGACCACGGTAGGCATCTTCACCATTGCTGTC
  GTGAGCAGCATCGTCCTGACGTCACTGGTCTGGGTGTGCATCATCTACCAGACCAGGAAG
  AAGAGTGAAGAGTACAGTGTCACCAACACAGATGAAACCGTCGTGCCACCAGATGTTCCA
  AGCTACCTCTCTTCTCAGGGGACCCTTTCTGACCGACAAGAAACCGTGGTCAGGACCGAG
  GGTGGCCCTCAGGCCAATGGGCACATTGAGAGCAATGGTGTGTGTCCAAGAGATGCAAGC
  CACTTTCCAGAGCCCGACACTCACAGCGTTGCCTGCAGGCAGCCAAAGCTCTGTGCTGGG
  TCTGCGTATCACAAAGAGCCGTGGAAAGCGATGGAGAAAGCTGAAGGGACACCTGGGCCA
  CATAAGATGGAACACGGTGGCCGGGTCGTATGCAGTGACTGCAACACCGAAGTGGACTGT
  TACTCCAGGGGACAAGCCTTCCACCCCCAGCCTGTGTCCAGAGACAGCGCACAGCCAAGT
  GCGCCAAATGGCCCGGAGCCGGGTGGGAGTGACCAAGAGCATTCTCCACATCACCAGTGC
  AGCAGGACTGCCGCTGGGTCCTGCCCCGAGTGCCAAGGGTCGCTCTACCCCAGTAACCAC
  GATAGAATGCTGACGGCTGTGAAGAAAAAGCCAATGGCATCTCTAGATGGGAAAGGGGAT
  TCTTCCTGGACTTTAGCAAGGTTGTATCACCCGGACTCCACAGAGCTACAGCCTGCATCT
  TCATTAACTTCAGGCAGTCCAGAGCGCGCGGAAGCCCAGTACTTGCTTGTTTCCAATGGC
  CACCTCCCCAAAGCATGTGACGCCAGTCCCGAGTCCACGCCACTGACAGGACAGCTCCCC
  GGGAAACAGAGGGTGCCACTGCTGTTGGCACCAAAAAGCTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_015541
• Insert Size: 3300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_015541.2, NP_056356.2
• RefSeq Size: 4812 bp
• RefSeq ORF: 3282 bp
• Locus ID: 26018
• UniProt ID: Q96JA1
• Cytogenetics: 3p14.1
• Domains: LRRNT, LRRCT, LRR, ig, LRR_TYP, IGc2, IG, LRR_SD22, LRR_PS
• Protein Families: Transmembrane
• Gene Summary: Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.[UniProtKB/Swiss-Prot Function]