AMHR2 (NM_020547) Human Untagged Clone

CAT#: SC314059

AMHR2 (untagged)-Human anti-Mullerian hormone receptor, type II (AMHR2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AMHR2
• Synonyms: AMHR; MISR2; MISRII; MRII
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_020547 edited
  CAGCTGTGCTGGCTTATGCTCTTCTCCTTCTGCTGCTGCCATCCTCCAGCAAGATGCTAG
  GGTCTTTGGGGCTTTGGGCATTACTTCCCACAGCTGTGGAAGCACCCCCAAACAGGCGAA
  CCTGTGTGTTCTTTGAGGCCCCTGGAGTGCGGGGAAGCACAAAGACACTGGGAGAGCTGC
  TAGATACAGGCACAGAGCTCCCCAGAGCTATCCGCTGCCTCTACAGCCGCTGCTGCTTTG
  GGATCTGGAACCTGACCCAAGACCGGGCACAGGTGGAAATGCAAGGATGCCGAGACAGTG
  ATGAGCCAGGCTGTGAGTCCCTCCACTGTGACCCAAGTCCCCGAGCCCACCCCAGCCCTG
  GCTCCACTCTCTTCACCTGCTCCTGTGGCACTGACTTCTGCAATGCCAATTACAGCCATC
  TGCCTCCTCCAGGGAGCCCTGGGACTCCTGGCTCCCAGGGTCCCCAGGCTGCCCCAGGTG
  AGTCCATCTGGATGGCACTGGTGCTGCTGGGGCTGTTCCTCCTCCTCCTGCTGCTGCTGG
  GCAGCATCATCTTGGCCCTGCTACAGCGAAAGAACTACAGAGTGCGAGGTGAGCCAGTGC
  CAGAGCCAAGGCCAGACTCAGGCAGGGACTGGAGTGTGGAGCTGCAGGAGCTGCCTGAGC
  TGTGTTTCTCCCAGCAGGTAATCCGGGAAGGAGGTCATGCAGTGGTTTGGGCCGGGCAGC
  TGCAAGGAAAACTGGTTGCCATCAAGGCCTTCCCACCGAGGTCTGTGGCTCAGTTCCAAG
  CTGAGAGAGCATTGTACGAACTTCCAGGCCTACAGCACGACCACATTGTCCGATTTATCA
  CTGCCAGCCGGGGGGGTCCTGGCCGCCTGCTCTCTGGGCCCCTGCTGGTACTGGAACTGC
  ATCCCAAGGGCTCCCTGTGCCACTACTTGACCCAGTACACCAGTGACTGGGGAAGTTCCC
  TGCGGATGGCACTGTCCCTGGCCCAGGGCCTGGCATTTCTCCATGAGGAGCGCTGGCAGA
  ATGGCCAAAATAAACCAGGTATTGCCCACCGAGATCTGAGCAGCCAGAATGTGCTCATTC
  GGGAAGATGGATCGTGTGCCATTGGAGACCTGGGCCTTGCCTTGGTGCTCCCTGGCCTCA
  CTCAGCCCCCTGCCTGGACCCCTACTCAACCACAAGGCCCAGCTGCCATCATGGAAGCTG
  GCACCCAGAGGTACATGGCACCAGAGCTCTTGGACAAGACTCTGGACCTACAGGATTGGG
  GCATGGCCCTCCGACGAGCTGATATTTACTCTTTGGCTCTGCTCCTGTGGGAGATACTGA
  GCCGCTGCCCAGATTTGAGGCCTGACAGCAGTCCACCACCCTTCCAACTGGCCTATGAGG
  CAGAACTGGGCAATACCCCTACCTCTGATGAGCTATGGGCCTTGGCAGTGCAGGAGAGGA
  GGCGTCCCTACATCCCATCCACCTGGCGCTGCTTTGCCACAGACCCTGATGGGCTGAGGG
  AGCTCCTAGAAGACTGTTGGGATGCAGACCCAGAAGCACGGCTGACAGCTGAGTGTGTAC
  AGCAGCGCCTGGCTGCCTTGGCCCATCCTCAAGAGAGCCACCCCTTTCCAGAGAGCTGTC
  CACGTGGCTGCCCACCTCTCTGCCCAGAAGACTGTACTTCAATTCCTGCCCCTACCATCC
  TCCCCTGTAGGCCTCAGCGGAGTGCCTGCCACTTCAGCGTTCAGCAAGGCCCTTGTTCCA
  GGAATCCTCAGCCTGCCTGTACCCTTTCTCCTGTGTAAATATGCAGTTTATGTGTCATCA
  ATGTACATGCCAACATAAATATGGCGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020547 unedited
  GTTCAAATTTTGTAATACGACTCACTATAGNNGGCGGCCGNCGNNNATTNNCGCCCTTCA
  GCTGTGCTGGCTTATGCTCTTCTCCTTCTGCTGCTGCCATCCTCCAGCAAGATGCTAGGG
  TCTTTGGGGCTTTGGGCATTACTTCCCACAGCTGTGGAAGCACCCCCAAACAGGCGAACC
  TGTGTGTTCTTTGAGGCCCCTGGAGTGCGGGGAAGCACAAAGACACTGGGAGAGCTGCTA
  GATACAGGCACAGAGCTCCCCAGAGCTATCCGCTGCCTCTACAGCCGCTGCTGCTTTGGG
  ATCTGGAACCTGACCCAAGACCGGGCACAGGTGGAAATGCAAGGATGCCGAGACAGTGAT
  GAGCCAGGCTGTGAGTCCCTCCACTGTGACCCAAGTCCCCGAGCCCACCCCAGCCCTGGC
  TCCACTCTCTTCACCTGCTCCTGTGGCACTGACTTCTGCAATGCCAATTACAGCCATCTG
  CCTCCTCCAGGGAGCCCTGGGACTCCTGGCTCCCAGGGTCCCCAGGCTGCCCCAGGTGAG
  TCCATCTGGATGGCACTGGTGCTGCTGGNGCTGTTCCTCCTCCTCCTGCTGCTGCTGGGC
  AGCATCATCTTGGCCCTGCTACAGCGAAAGAACTACAGAGTGCGAGGTGAGCCAGTGCCA
  GAGCCAAGGCCAGACTCANGCAGGGACTGGAGTGTGGAGCTGCNAGAGCTGCCTGAGCTG
  TGNTTCTCCCAGCAGGTAATCCGGGAAGGGAGTCATGCAGTGTTTTGGGCCGGGCAGCTG
  CAAGGAAAACTGGTTGCCATCAAGCCCTTNCCACCGAGGTCTGTGGCTCAGTTCCCAACT
  GAGAAAGCATTGTACGAACTTNCAGGGCTACAGGACGACCACATTGTGCGATTTTTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020547 unedited
  CCCCATTGGNGATGGCAACTTCCAGGNCCAGGNAAAGCACTNNGGGGNNAGGGGTNCACA
  GGGATGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCG
  ACAAGCTTGATATCGGTACCAGATCTGAATTCGCCCTTTCGCCATATTTATGTTGGCATG
  TACATTGATGACACATAAACTGCATATTTACACAGGAGAAAGGGTACAGGCAGGCTGAGG
  ATTCCTGGAACAAGGGCCTTGCTGAACGCTGAAGTGGCAGGCACTCCGCTGAGGCCTACA
  GGGGAGGATGGTAGGGGCAGGAATTGAAGTACAGTCTTCTGGGCAGAGAGGTGGGCAGCC
  ACGTGGACAGCTCTCTGGAAAGGGGTGGCTCTCTTGAGGATGGGCCAAGGCAGCCAGGCG
  CTGCTGTACACACTCAGCTGTCAGCCGTGCTTCTGGGTCTGCATCCCAACAGTCTTCTAG
  GAGCTCCCTCAGCCCATCAGGGTCTGTGGCAAAGCAGCGCCAGGTGGATGGGATGTAGGG
  ACGCCTCCTCTCCTGCACTGCCAAGGCCCATAGCTCATCAGAGGTAGGGGTATTGCCCAG
  TTCTGCCTCATAGGCCAGTTGGAAGGGTGGTGGACTGCTGTCAGGCCTCANATCTGGGCA
  GCGGCTCAGTATCTCCCACAGGAGCAGAGCCAAAGAGTAAATATCAGCTCGTCGGAAGGC
  CATGCCCCAATCCTGTNAGTCCAGAGTCTTGTCCAAGAGCTCTGGTGCCATGTACCTCTG
  GGTGCCAGCTTCCATGATGGCAGCTGGGCCTTGTGGTTGAGTANGGGTCCCAGCAGGGGG
  CTGAGTGAAGCCAGGGAGCACCAAAGGCAGGNCCCAGTCTNCAATGGCACACGATCCCAT
  CTCCCGAATGAGCACAATTCTGC
  
• Restriction Sites: Please inquire
• ACCN: NM_020547
• Insert Size: 1800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: There is 1 nucleotide difference between the OriGene clone and the NCBI reference ORF. These result in the substitution of 1 aa and insertion of 1 aa.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_020547.1, NP_065434.1
• RefSeq Size: 1855 bp
• RefSeq ORF: 1722 bp
• Locus ID: 269
• UniProt ID: Q16671
• Cytogenetics: 12q13.13
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
• Gene Summary: This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).